MMP7 抗体 (AA 18-267)
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北京 101111
Quick Overview for MMP7 抗体 (AA 18-267) (ABIN3021103)
抗原
See all MMP7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-267
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序列
- LPLPQEAGGM SELQWEQAQD YLKRFYLYDS ETKNANSLEA KLKEMQKFFG LPITGMLNSR VIEIMQKPRC GVPDVAEYSL FPNSPKWTSK VVTYRIVSYT RDLPHITVDR LVSKALNMWG KEIPLHFRKV VWGTADIMIG FARGAHGDSY PFDGPGNTLA HAFAPGTGLG GDAHFDEDER WTDGSSLGIN FLYAATHELG HSLGMGHSSD PNAVMYPTYG NGDPQNFKLS QDDIKGIQKL YGKRSNSRKK
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 18-267 of human MMP7 (NP_002414.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
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别名
- MMP7
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背景
- This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.,MMP7,MMP-7,MPSL1,PUMP-1,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,MMP7
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分子量
- 29 kDa
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基因ID
- 4316
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UniProt
- P09237
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途径
- Production of Molecular Mediator of Immune Response
抗原
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