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Interleukin 17a 抗体 (AA 24-155)

This anti-Interleukin 17a antibody is a 兔 多克隆 antibody detecting Interleukin 17a in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 7+ publications.
产品编号 ABIN3021082
发货至: 中国

Quick Overview for Interleukin 17a 抗体 (AA 24-155) (ABIN3021082)

抗原

See all Interleukin 17a (IL17A) 抗体
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

适用

  • 84
  • 46
  • 19
  • 7
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  • 5
  • 4
  • 3
  • 3
  • 3
  • 3

宿主

  • 65
  • 38
  • 16
  • 5
  • 2
  • 2

克隆类型

  • 70
  • 57
  • 1
多克隆

标记

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  • 21
  • 14
  • 8
  • 7
  • 4
  • 1
  • 1
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This Interleukin 17a antibody is un-conjugated

应用范围

  • 75
  • 55
  • 27
  • 24
  • 14
  • 11
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  • 8
  • 8
  • 8
  • 5
  • 5
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  • 1
  • 1
  • 1
  • 1
  • 1
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-155

    序列

    GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG CTCVTPIVHH VA

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 24-155 of human IL17A (NP_002181.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhang, Zhao, Song, Yang, Zhang, Zhang, Li: "Differential Health Effects of Constant versus Intermittent Exposure to Formaldehyde in Mice: Implications for Building Ventilation Strategies." in: Environmental science & technology, Vol. 52, Issue 3, pp. 1551-1560, (2018) (PubMed).

    Dong, Xu, Yang, Shi, Jiang, Chen, Song, Wang: "Associations of Functional MicroRNA Binding Site Polymorphisms in IL23/Th17 Inflammatory Pathway Genes with Gastric Cancer Risk." in: Mediators of inflammation, Vol. 2017, pp. 6974696, (2018) (PubMed).

    Ma, Pan, Zhou, Liu, Wang: "Hyperforin protects against acute cerebral ischemic injury through inhibition of interleukin-17A-mediated microglial activation." in: Brain research, Vol. 1678, pp. 254-261, (2018) (PubMed).

    Liu, Fan, Zheng, Chen, Zhang, Li: "The mediation of interleukin-17 and chemokine ligand 2 in pelvic pain of experimental autoimmune prostatitis." in: Experimental and therapeutic medicine, Vol. 14, Issue 1, pp. 51-58, (2017) (PubMed).

    Yao, Weng, Zhang, Feng, Lin, Yao: "Interleukin-17A Acts to Maintain Neuropathic Pain Through Activation of CaMKII/CREB Signaling in Spinal Neurons." in: Molecular neurobiology, Vol. 53, Issue 6, pp. 3914-3926, (2016) (PubMed).

    Zhang, Mao, Zhou, Cheng, Lin: "IL-17A contributes to brain ischemia reperfusion injury through calpain-TRPC6 pathway in mice." in: Neuroscience, Vol. 274, pp. 419-28, (2014) (PubMed).

    Zhang, Wu, Weng, Zhou, Feng, Lin: "Glycyrrhizin protects brain against ischemia-reperfusion injury in mice through HMGB1-TLR4-IL-17A signaling pathway." in: Brain research, Vol. 1582, pp. 176-86, (2014) (PubMed).

  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    IL17A

    背景

    The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.,IL17A,CTLA-8,CTLA8,IL-17,IL-17A,IL17,Cancer,Tumor immunology,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL17A

    分子量

    17 kDa

    基因ID

    3605

    UniProt

    Q16552
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