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Estrogen Receptor alpha 抗体 (AA 1-190)

ESR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3020904
发货至: 中国
  • 抗原 See all Estrogen Receptor alpha (ESR1) 抗体
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    抗原表位
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    AA 1-190
    适用
    • 465
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    宿主
    • 373
    • 99
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    克隆类型
    • 356
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    多克隆
    标记
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    This Estrogen Receptor alpha antibody is un-conjugated
    应用范围
    • 342
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    Western Blotting (WB)
    序列
    MTMTLHTKAS GMALLHQIQG NELEPLNRPQ LKIPLERPLG EVYLDSSKPA VYNYPEGAAY EFNAAAAANA QVYGQTGLPY GPGSEAAAFG SNGLGGFPPL NSVSPSPLML LHPPPQLSPF LQPHGQQVPY YLENEPSGYT VREAGPPAFY RPNSDNRRQG GRERLASTND KGSMAMESAK ETRYCAVCND
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human ESRalpha (ESR1) (NP_000116.2).
    亚型
    IgG
    Top Product
    Discover our top product ESR1 Primary Antibody
  • 应用备注
    WB,1:1000 - 1:4000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    别名
    ESR1 (ESR1 产品)
    背景
    This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.,ESR1,ER,ESR,ESRA,ESTRR,Era,NR3A1,ER alpha,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Signal Transduction,MAPK-Erk Signaling Pathway,ESR1
    分子量
    35 kDa/47 kDa/53 kDa/66 kDa
    基因ID
    2099
    UniProt
    P03372
    途径
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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