CARD8 抗体 (AA 1-200)
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Quick Overview for CARD8 抗体 (AA 1-200) (ABIN3020898)
抗原
See all CARD8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-200
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序列
- MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CARD8 (NP_003796.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
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别名
- CARD8
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背景
- The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.,CARD8,CARDINAL,DACAR,DAKAR,NDPP,NDPP1,TUCAN,Cell Biology & Developmental Biology,Apoptosis,Caspases,CARD8
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分子量
- 32 kDa/44 kDa/48 kDa/55 kDa/60 kDa
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基因ID
- 22900
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UniProt
- Q9Y2G2
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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