NEFL 抗体 (AA 400-543)
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北京 101111
Quick Overview for NEFL 抗体 (AA 400-543) (ABIN3020809)
抗原
See all NEFL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-543
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序列
- LSFTSVGSIT SGYSQSSQVF GRSAYGGLQT SSYLMSTRSF PSYYTSHVQE EQIEVEETIE AAKAEEAKDE PPSEGEAEEE EKDKEEAEEE EAAEEEEAAK EESEEAKEEE EGGEGEEGEE TKEAEEEEKK VEGAGEEQAA KKKD
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 400-543 of human Neurofilament L (NP_006149.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- NEFL (Neurofilament, Light Polypeptide (NEFL))
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别名
- NEFL
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背景
- Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.,NEFL,CMT1F,CMT2E,NF-L,NF68,NFL,PPP1R110,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Stem Cells,Neural Stem Cell marker,Neuron marker,Axon marker,NEFL
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分子量
- 61 kDa
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基因ID
- 4747
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UniProt
- P07196
抗原
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