CD24 抗体
(6 references)Quick Overview for CD24 抗体 (ABIN302076)
抗原
See all CD24 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD24 Purified
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特异性
- The antibody SN3 reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cell malignancies. It is not expressed on human thymocytes.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Glycoproteins purified from human NALM-1 cell line.
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亚型
- IgG1 kappa
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anti-CD24 Molecule (CD24) antibody (FITC)
CD24 适用: 人 FACS 宿主: 小鼠 Monoclonal SN3 FITC
anti-CD24 Molecule (CD24) (AA 15-80) antibodyCD24 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4F4E10 unconjugated
anti-CD24 Molecule (CD24) (AA 60-80) antibodyCD24 适用: 人, 小鼠, 大鼠 IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD24 Molecule (CD24) (AA 1-80) antibodyCD24 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD24 Molecule (CD24) (AA 15-80) antibodyCD24 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-CD24 Molecule (CD24) antibody (APC)CD24 适用: 人 FACS 宿主: 小鼠 Monoclonal SN3 APC
anti-CD24 Molecule (CD24) antibody (PE)CD24 适用: 人 FACS 宿主: 小鼠 Monoclonal SN3 PE
anti-CD24 Molecule (CD24) (AA 30-60) antibodyCD24 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD24 Molecule (CD24) antibodyCD24 适用: 人, Chimpanzee FACS, IHC (fro) 宿主: 小鼠 Monoclonal SN3 unconjugated
anti-CD24 Molecule (CD24) antibodyCD24 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C4 unconjugated
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应用备注
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Immunohistochemistry (frozen sections): Positive tissue: tonsil.
Flow cytometry: Recommended dilution: 1-12 μg/mL -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Analysis of B-cell subpopulations in monoclonal gammopathies." in: Clinical lymphoma, myeloma & leukemia, Vol. 15, Issue 4, pp. e61-71, (2015) (PubMed).
: "Redirected T cells that target pancreatic adenocarcinoma antigens eliminate tumors and metastases in mice." in: Gastroenterology, Vol. 143, Issue 5, pp. 1375-84.e1-5, (2012) (PubMed).
: "The human fetal omentum: a site of B cell generation." in: The Journal of experimental medicine, Vol. 175, Issue 2, pp. 397-404, (1992) (PubMed).
: "Signal transduction in lymphocytic and myeloid cells via CD24, a new member of phosphoinositol-anchored membrane molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 2, pp. 638-41, (1990) (PubMed).
: "Follicular mantle zone cell subpopulations detected by monoclonal antibody SN3." in: Hematological oncology, Vol. 4, Issue 4, pp. 251-9, (1987) (PubMed).
: "New monoclonal antibodies SN3, SN3a, and SN3b directed to sialic acid of glycoprotein on human non-T leukemia cells." in: Experimental hematology, Vol. 14, Issue 9, pp. 850-5, (1986) (PubMed).
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: "Analysis of B-cell subpopulations in monoclonal gammopathies." in: Clinical lymphoma, myeloma & leukemia, Vol. 15, Issue 4, pp. e61-71, (2015) (PubMed).
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- CD24 (CD24 Molecule (CD24))
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别名
- CD24
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背景
- CD24 Molecule,CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.,HSA, nectadorin, SCLC4
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基因ID
- 100133941
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UniProt
- P25063
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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