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HDAC1 抗体 (AA 393-482)

This 兔多克隆 antibody specifically detects HDAC1 in WB, IHC, IF 和 IP. It exhibits reactivity toward 人. It has been mentioned in 3+ publications

Confocal immunofluorescence analysis of L929 cells using HD Polyclonal Antibody (ABIN3020753, ABIN3020754, ABIN3020755 and ABIN6213707) at dilution of 1:200. (HDAC1 抗体 (AA 393-482))

Immunohistochemistry of paraffin-embedded human prostate cancer using HDAC1 antibody. (HDAC1 抗体 (AA 393-482))

IHC (p)

Immunofluorescence analysis of A549 cells using HDAC1 antibody. (HDAC1 抗体 (AA 393-482))

Immunohistochemistry of paraffin-embedded human lung cancer using HDAC1 antibody. (HDAC1 抗体 (AA 393-482))

IHC (p)

Immunofluorescence analysis of A549 cell using HDAC1 antibody. (HDAC1 抗体 (AA 393-482))

Immunohistochemistry of paraffin-embedded human stomach using HDAC1 antibody. (HDAC1 抗体 (AA 393-482))

IHC (p)

Immunohistochemistry of paraffin-embedded human esophagus using HDAC1 antibody. (HDAC1 抗体 (AA 393-482))

IHC (p)

8 images

(3 references)

产品编号 ABIN3020754

发货至: 中国

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Quick Overview for HDAC1 抗体 (AA 393-482) (ABIN3020754)

抗原

See all HDAC1 抗体

HDAC1 (Histone Deacetylase 1 (HDAC1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This HDAC1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Discover our top product HDAC1 Primary Antibody

抗原表位
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AA 393-482

序列

SGDEDEDDPD KRISICSSDK RIACEEEFSD SEEEGEGGRK NSSNFKKAKR VKTEDEKEKD PEEKKEVTEE EKTKEEKPEA KGVKEEVKLA

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 393-482 of human HDAC1 (NP_004955.2).

亚型

IgG
anti-Histone Deacetylase 1 (HDAC1) antibody
KO Validated HDAC1 适用: 人 WB, IF, ICC, IP, IHC (p), ChIP, IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibody
HDAC1 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 5C11 unconjugated

anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibody
HDAC1 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal E22 unconjugated

anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibody
HDAC1 适用: 人 IHC, ELISA, IF, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 1 (HDAC1) antibody
KO Validated HDAC1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Histone Deacetylase 1 (HDAC1) (AA 1-482) antibody
HDAC1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A11 unconjugated

anti-Histone Deacetylase 1 (HDAC1) (AA 450-482) antibody
HDAC1 适用: 人 WB, IHC, ELISA, IF, FM, MA 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 1 (HDAC1) (C-Term) antibody
Verified HDAC1 适用: 人, 小鼠 WB, ELISA, IF, ChIP 宿主: 山羊 Polyclonal unconjugated

anti-Histone Deacetylase 1 (HDAC1) (Middle Region) antibody
HDAC1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 1 (HDAC1) (C-Term) antibody
HDAC1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:100,IP,1:50 - 1:100

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Fan, Li, Wang, Emerson, Xu: "A Novel ZIP4-HDAC4-VEGFA Axis in High-Grade Serous Ovarian Cancer." in: Cancers, Vol. 13, Issue 15, (2021) (PubMed).

Tao, Hsu, Ma, Cheng, Lee: "Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Aβ toxicity in a mouse model of Alzheimer's disease." in: Cell death and differentiation, Vol. 24, Issue 4, pp. 597-614, (2018) (PubMed).

Zeng, Huang, Wang, Wu, Wu, Huang: "Galangin-induced down-regulation of BACE1 by epigenetic mechanisms in SH-SY5Y cells." in: Neuroscience, Vol. 294, pp. 172-81, (2015) (PubMed).
抗原

HDAC1 (Histone Deacetylase 1 (HDAC1))

别名

HDAC1

背景

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.,GON-10,HD1,RPD3,RPD3L1,HDAC1,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Deacetylation,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,G1/S Checkpoint,Notch Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Stem Cells,Cardiovascular,Heart,Hypertrophy,HDAC1

分子量

55 kDa

基因ID

3065

UniProt

Q13547

途径

Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis