FGF2 抗体 (AA 143-288)
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北京 101111
Quick Overview for FGF2 抗体 (AA 143-288) (ABIN3020745)
抗原
See all FGF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 143-288
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序列
- PALPEDGGSG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH IKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTD ECFFFERLES NNYNTYRSRK YTSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 143-288 of human FGF2 (NP_001997.5).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Role and regulation of growth plate vascularization during coupling with osteogenesis in tibial dyschondroplasia of chickens." in: Scientific reports, Vol. 8, Issue 1, pp. 3680, (2018) (PubMed).
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: "Role and regulation of growth plate vascularization during coupling with osteogenesis in tibial dyschondroplasia of chickens." in: Scientific reports, Vol. 8, Issue 1, pp. 3680, (2018) (PubMed).
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- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
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别名
- FGF2
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背景
- The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.,BFGF,FGF-2,FGFB,HBGF-2,Basic FGF,FGF2,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Neuroscience,Stem Cells,Neural Stem Cells,Cardiovascular,Angiogenesis,Angiogenic growth factors,FGF2
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分子量
- 17 kDa/21 kDa/22 kDa/30 kDa
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基因ID
- 2247
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UniProt
- P09038
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
抗原
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