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DDIT3 抗体 (C-Term)

This anti-DDIT3 antibody is a 兔 多克隆 antibody detecting DDIT3 in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN3020710
发货至: 中国

Quick Overview for DDIT3 抗体 (C-Term) (ABIN3020710)

抗原

See all DDIT3 抗体
DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

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宿主

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克隆类型

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多克隆

标记

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This DDIT3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    序列

    GRTRKRKQSG HSPARAGKQR MKEKEQENER KVAQLAEENE RLKQEIERLT REVEATRRAL IDRMVNLHQA

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human DDIT3/CHOP (NP_004074.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhang, Yan, Wang, Dai, Wang, Cai: "Autophagy May Protect Against Parenteral Nutrition-Associated Liver Disease by Suppressing Endoplasmic Reticulum Stress." in: JPEN. Journal of parenteral and enteral nutrition, Vol. 43, Issue 1, pp. 96-106, (2019) (PubMed).

    Anasa, Manickam, Talwar, Ravanan: "Identification of ASB7 as ER stress responsive gene through a genome wide in silico screening for genes with ERSE." in: PLoS ONE, Vol. 13, Issue 4, pp. e0194310, (2018) (PubMed).

    Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).

  • 抗原

    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

    别名

    DDIT3

    背景

    This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.,DDIT3,CEBPZ,CHOP,CHOP-10,CHOP10,GADD153,C/EBPzeta,DDIT3 / CHOP,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Protein folding,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Stem Cells,Embryonic Stem Cells,DDIT3

    分子量

    19 kDa/21 kDa

    基因ID

    1649

    UniProt

    P35638

    途径

    Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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