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GDF15 抗体 (AA 49-308)

This anti-GDF15 antibody is a 兔 多克隆 antibody detecting GDF15 in WB, IHC, IP 和 IF. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN3020659
发货至: 中国

Quick Overview for GDF15 抗体 (AA 49-308) (ABIN3020659)

抗原

See all GDF15 抗体
GDF15 (Growth Differentiation Factor 15 (GDF15))

适用

  • 101
  • 38
  • 24
  • 1
  • 1

宿主

  • 96
  • 15
  • 3
  • 3
  • 1

克隆类型

  • 94
  • 21
  • 2
多克隆

标记

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  • 1
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This GDF15 antibody is un-conjugated

应用范围

  • 93
  • 57
  • 48
  • 15
  • 13
  • 13
  • 13
  • 8
  • 7
  • 5
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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 13
    • 10
    • 7
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 49-308

    序列

    EDSRFRELRK RYEDLLTRLR ANQSWEDSNT DLVPAPAVRI LTPEVRLGSG GHLHLRISRA ALPEGLPEAS RLHRALFRLS PTASRSWDVT RPLRRQLSLA RPQAPALHLR LSPPPSQSDQ LLAESSSARP QLELHLRPQA ARGRRRARAR NGDHCPLGPG RCCRLHTVRA SLEDLGWADW VLSPREVQVT MCIGACPSQF RAANMHAQIK TSLHRLKPDT VPAPCCVPAS YNPMVLIQKT DTGVSLQTYD DLLAKDCHCI

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 49-308 of human GDF15 (NP_004855.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200,IP,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Yang, Dai, Lu, Zhang, Keller: "Prostate cancer promotes a vicious cycle of bone metastasis progression through inducing osteocytes to secrete GDF15 that stimulates prostate cancer growth and invasion." in: Oncogene, Vol. 38, Issue 23, pp. 4540-4559, (2019) (PubMed).

    Han, Dai, Yousafzai, Wang, Wang, Zhou, Lu, Xu, Feng, Jin, Wang: "CXXC4 activates apoptosis through up-regulating GDF15 in gastric cancer." in: Oncotarget, Vol. 8, Issue 61, pp. 103557-103567, (2017) (PubMed).

    Tsui, Hsu, Chung, Lin, Feng, Lee, Chang, Juang: "Growth differentiation factor-15: a p53- and demethylation-upregulating gene represses cell proliferation, invasion, and tumorigenesis in bladder carcinoma cells." in: Scientific reports, Vol. 5, pp. 12870, (2016) (PubMed).

  • 抗原

    GDF15 (Growth Differentiation Factor 15 (GDF15))

    别名

    GDF15

    背景

    The protein encoded by this gene belongs to the transforming growth factor-beta (TGF-beta) family. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress reponse program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.,GDF15,GDF-15,MIC-1,MIC1,NAG-1,PDF,PLAB,PTGFB,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,Immunology & Inflammation,Cytokines,Cardiovascular,Heart,Hypertrophy,GDF15

    分子量

    34 kDa

    基因ID

    9518

    UniProt

    Q99988

    途径

    SARS-CoV-2 Protein Interactome
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