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GAPDH 抗体

Name: GAPDH 抗体
Brand: antibodies-online
SKU: ABIN1512934
Availability: OutOfStock

This anti-GAPDH antibody is a 小鼠单克隆 antibody detecting GAPDH in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 46+ publications.

Western blot analysis of extracts of various cell lines, using GAPDH antibody at 1:2000 dilution. (GAPDH 抗体)

Immunohistochemistry of paraffin-embedded rat lung using GAPDH Mouse mAb (ABIN3020540, ABIN3020541, ABIN3020542 and ABIN1512934) at dilution of 1:100 (40x lens). (GAPDH 抗体)

IHC

Western blot analysis of extracts of various cell lines, using GAPDH antibody. (GAPDH 抗体)

Compared with CS, EGFL7 is highly expressed in OS. (GAPDH 抗体)

YAP1 expression levels in NSCLC tissues and NSCLC cell lines. (GAPDH 抗体)

EMT-related marker expression in A549 cells with YAP1 overexpression or silencing. (GAPDH 抗体)

TEAD is involved in YAP1-induced EMT in A549 cells. (GAPDH 抗体)

Inhibiting the co-transcription complex YAP/TEAD reverses A549 cell proliferation, migration, and invasion induced by TGF-β1. (GAPDH 抗体)

Slug is regulated by the co-transcriptional complex YAP1/TEAD in the EMT program of A549 cells. (GAPDH 抗体)

The expressions of H19 and integrin β3 (ITGB3) decrease in human embryonic chorion tissue of spontaneous abortion. (GAPDH 抗体)

Enhanced mitochondrial fission in STs of RA patients correlates with disease severity. (GAPDH 抗体)

DNM1L deficiency alters mitochondria morphology and mitochondrial membrane potential in FLSs. (GAPDH 抗体)

DNM1L deficiency in FLSs reduces their viability and production of pro-inflammatory cytokines, and increases apoptosis. (GAPDH 抗体)

DNM1L deficiency reduces ROS production and autophagy in FLS. (GAPDH 抗体)

DNM1L deficiency attenuates the IL-1β-induced NF-κB activation in FLSs. (GAPDH 抗体)

HMGB1 was a direct target of miR-339-5p. (GAPDH 抗体)

The effects of miR-339-5p and HMGB1-siRNA on LPS-induced RAW264. (GAPDH 抗体)

Effects of paeonol on IKK-β in LPS-induced RAW264. (GAPDH 抗体)

ISG20 promoted ccRCC cell proliferation in vitro. (GAPDH 抗体)

ZNF139 and its circRNA (circZNF139) activates PI3K/AKT signaling pathway in BC cells. (GAPDH 抗体)

Astrocytes were activated and mainly expressed as the A1 phenotype in the spinal cord after SMIR. (GAPDH 抗体)

Minocycline reverted the A1/A2 ratio of reactive astrocytes and relieved mechanical allodynia in rats after SMIR. (GAPDH 抗体)

The CXCR7 and PI3K/Akt signaling pathways are involved in CPSP in the dorsal horn of the spinal cord. (GAPDH 抗体)

The combination of BKM120 and TH588 synergistically induces oxidative DNA damage and apoptosis. (GAPDH 抗体)

Establishment and confirmation of radiation-induced lung fibrosis in a murine model. (GAPDH 抗体)

Increased DIO2 expression in lung tissue after radiation treatment and inhibition of the TGF-β1 signaling pathway by thyroid hormone. (GAPDH 抗体)

Immunohistochemistry of paraffin-embedded human liver cancer using GAPDH Mouse mAb (ABIN3020540, ABIN3020541, ABIN3020542 and ABIN1512934) at dilution of 1:100 (40x lens). (GAPDH 抗体)

IHC

Immunofluorescence analysis of NIH/3T3 cells using GAPDH Mouse mAb (ABIN3020540, ABIN3020541, ABIN3020542 and ABIN1512934) at dilution of 1:100 (40x lens). (GAPDH 抗体)

Immunohistochemistry of paraffin-embedded mouse stomach using GAPDH Mouse mAb (ABIN3020540, ABIN3020541, ABIN3020542 and ABIN1512934) at dilution of 1:100 (40x lens). (GAPDH 抗体)

IHC

41 images

(46 references)

产品编号 ABIN1512934

发货至: 中国

Quick Overview for GAPDH 抗体 (ABIN1512934)

抗原

See all GAPDH 抗体

GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This GAPDH antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product GAPDH Primary Antibody

交叉反应

人, 小鼠, 大鼠

产品特性

Loading control Antibodies

纯化方法

Affinity purification

免疫原

Recombinant protein of human GAPDH

亚型

IgG
anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) antibody
GAPDH 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335) antibody
GAPDH 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (C-Term) antibody
Verified GAPDH 适用: 人, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (Internal Region) antibody
Verified GAPDH 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 226-335) antibody
GAPDH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C2 unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 136-335) antibody
GAPDH 适用: 人, 小鼠, 大鼠, 小鸡, 猴, 斑马鱼 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) antibody
GAPDH 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A10A10 unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 62-91), (N-Term) antibody
GAPDH 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB16537 unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 2-148) antibody
GAPDH 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal D1 unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 154-324) antibody
GAPDH 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:5000 - 1:20000,IHC,1:50 - 1:200,IF,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Wu, Xiong, Li, Yang, Ge et al.: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).

Han, Cai, Gao, Meng, Gao, Wu, Duan, Wang, Dinislam, Lin, Kang, Jiang: "Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma." in: Cancer letters, Vol. 419, pp. 280-290, (2019) (PubMed).

Zhang, Qian, Zheng, Qian, Wang, Thu, Zhang, Zhou, Tu, Liu, Li, Yang, Li, Xu: "Jujuboside A promotes Aβ clearance and ameliorates cognitive deficiency in Alzheimer's disease through activating Axl/HSP90/PPARγ pathway." in: Theranostics, Vol. 8, Issue 15, pp. 4262-4278, (2018) (PubMed).

Yu, Chen, Li, Yang, Zhang, Huangfu, Zheng, Zhao, Lv, Hong, Liang, Shan: "YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD." in: Cell death & disease, Vol. 9, Issue 5, pp. 464, (2018) (PubMed).

Peng, Wang, Shu, Yang, Wang, Ouyang, Shen, Hou, Zhao, Wang, Zhang, Liu, Zhao: "Raddeanin a Suppresses Glioblastoma Growth by Inducing ROS Generation and Subsequent JNK Activation to Promote Cell Apoptosis." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 47, Issue 3, pp. 1108-1121, (2018) (PubMed).

Nie, Huang, Deng, Bao, Liu, Feng, Wang, Chen, Qi, Pan: "The purine receptor P2X7R regulates the release of pro-inflammatory cytokines in human craniopharyngioma." in: Endocrine-related cancer, Vol. 24, Issue 6, pp. 287-296, (2018) (PubMed).

Wan, Ashraf, Ye, Duan, Zohaib, Wang, Chen, Zhu, Li, Chen, Cao: "MicroRNA-22 negatively regulates poly(I:C)-triggered type I interferon and inflammatory cytokine production via targeting mitochondrial antiviral signaling protein (MAVS)." in: Oncotarget, Vol. 7, Issue 47, pp. 76667-76683, (2018) (PubMed).

Wu, Lou, Ge, Xiong: "Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos." in: Scientific reports, Vol. 7, Issue 1, pp. 4022, (2018) (PubMed).

Lei, Pan, Li, Zhou, Zhang, He, Peng, Li, Sidhu, Chen, Hua: "H19 regulates the proliferation of bovine male germline stem cells via IGF-1 signaling pathway." in: Journal of cellular physiology, Vol. 234, Issue 1, pp. 915-926, (2018) (PubMed).

Dong, Xu, Yang, Shi, Jiang, Chen, Song, Wang: "Associations of Functional MicroRNA Binding Site Polymorphisms in IL23/Th17 Inflammatory Pathway Genes with Gastric Cancer Risk." in: Mediators of inflammation, Vol. 2017, pp. 6974696, (2018) (PubMed).

Li, Zhu, Yang, Dib-Hajj, Waxman, Yu, Xu, Cheng: "Nav1.7 is phosphorylated by Fyn tyrosine kinase which modulates channel expression and gating in a cell type-dependent manner." in: Molecular pain, Vol. 14, pp. 1744806918782229, (2018) (PubMed).

Zhang, Zhou, Huang, Yu, Zhang, Wang: "Placental mechanism of prenatal nicotine exposure-reduced blood cholesterol levels in female fetal rats." in: Toxicology letters, Vol. 296, pp. 31-38, (2018) (PubMed).

Sheng, Yu, Chen, Wang, Lu: "Infection of grass carp reovirus induced the expressional suppression of pro-viral Fibulin-4 in host cells." in: Fish & shellfish immunology, Vol. 77, pp. 294-297, (2018) (PubMed).

Zhang, Zhang, Deng, Zhang, Liu, Xin, Li, Xu: "Baicalin attenuates non-alcoholic steatohepatitis by suppressing key regulators of lipid metabolism, inflammation and fibrosis in mice." in: Life sciences, Vol. 192, pp. 46-54, (2018) (PubMed).

Liu, Song, Zhao, He, Wang, Chen, Xiang, Yi, Qi, Liu: "Antitumor Activity and Mechanism of a Reverse Transcriptase Inhibitor, Dapivirine, in Glioblastoma." in: Journal of Cancer, Vol. 9, Issue 1, pp. 117-128, (2018) (PubMed).

Liu, Zhang, Yao, Xie, Dai, Zhang, Zhou: "Serum extracellular vesicles promote proliferation of H9C2 cardiomyocytes by increasing miR-17-3p." in: Biochemical and biophysical research communications, Vol. 499, Issue 3, pp. 441-446, (2018) (PubMed).

Li, Zhou, Yang, Li, Zhang, Wang, Jiao: "SGK1 inhibits PM2.5-induced apoptosis and oxidative stress in human lung alveolar epithelial A549 cells." in: Biochemical and biophysical research communications, Vol. 496, Issue 4, pp. 1291-1295, (2018) (PubMed).

Ruan, Zhao, Zhao, Zhang, Shi, Pang: "Knockdown of long noncoding RNA MEG3 impairs VEGF-stimulated endothelial sprouting angiogenesis via modulating VEGFR2 expression in human umbilical vein endothelial cells." in: Gene, Vol. 649, pp. 32-39, (2018) (PubMed).

Qiu, Wu, Meng, Luo, Zhao, Sun, Gao: "GYY4137 protects against myocardial ischemia/reperfusion injury via activation of the PHLPP-1/Akt/Nrf2 signaling pathway in diabetic mice." in: The Journal of surgical research, Vol. 225, pp. 29-39, (2018) (PubMed).

Shen, Zhu, Kang, Tu, Li, Zhang, Qin, Yang, Guan: "Lanosterol Synthase Pathway Alleviates Lens Opacity in Age-Related Cortical Cataract." in: Journal of ophthalmology, Vol. 2018, pp. 4125893, (2018) (PubMed).

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抗原

GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

别名

GAPDH

背景

This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.,G3PD,GAPD,HEL-S-162eP,GAPDH,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,GAPDH

分子量

31 kDa/36 kDa

基因ID

2597

UniProt

P04406