TNFRSF10A 抗体 (PE)
(2 references)Quick Overview for TNFRSF10A 抗体 (PE) (ABIN302032)
抗原
See all TNFRSF10A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD261 PE
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特异性
- The mouse monoclonal antibody DR-4-02 recognizes an extracellular epitope of TRAIL-R1 (DR4), a human death receptor 4 expressed in most human tissues (spleen, peripheral blood leucocytes, thymus) and in a variety of tumour-derived cell lines.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1.
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亚型
- IgG1
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibody
TNFRSF10A 适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal DR-4-02 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibody (FITC)TNFRSF10A 适用: 人 FACS 宿主: 小鼠 Monoclonal DR-4-02 FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 269-468) antibodyTNFRSF10A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 269-468) antibodyTNFRSF10A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 105-204) antibodyTNFRSF10A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibodyTNFRSF10A 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibodyTNFRSF10A 适用: 人 FACS, IP, ICC, Func 宿主: 小鼠 Monoclonal DR-4-02 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (C-Term) antibodyTNFRSF10A 适用: 人 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibodyTNFRSF10A 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal TR1-02 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibody (APC)TNFRSF10A 适用: 人 FACS 宿主: 小鼠 Monoclonal DR-4-02 APC
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应用备注
- Flow cytometry: Recommended dilution: 2-5 μg/mL.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze.
Avoid prolonged exposure to light. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway." in: Carcinogenesis, Vol. 32, Issue 1, pp. 42-51, (2010) (PubMed).
: "Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane." in: Apoptosis : an international journal on programmed cell death, Vol. 13, Issue 3, pp. 423-36, (2008) (PubMed).
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: "Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway." in: Carcinogenesis, Vol. 32, Issue 1, pp. 42-51, (2010) (PubMed).
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- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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别名
- CD261
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背景
- TNF receptor superfamily member 10a,TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).,DR4, APO2, TNFRSF10A, TRAILR1, TRAIL-R1
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基因ID
- 8797
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UniProt
- O00220
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途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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