LIMK2 抗体 (pThr505)
Quick Overview for LIMK2 抗体 (pThr505) (ABIN3020313)
抗原
See all LIMK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr505
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Phosphorylated Antibodies
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免疫原
- A phospho specific peptide corresponding to residues surrounding T505 of human LIMK2
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亚型
- IgG
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anti-LIM Domain Kinase 2 (LIMK2) (pSer283) antibody
LIMK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibodyLIMK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2H2-E11 unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (pThr505) antibodyLIMK2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibodyLIMK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) antibodyLIMK2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (Ser283) antibodyLIMK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-240) antibodyLIMK2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 181-193) antibodyVerified LIMK2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibodyLIMK2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-240) antibodyLIMK2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- LIMK2 (LIM Domain Kinase 2 (LIMK2))
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别名
- LIMK2
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背景
- There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene.,LIMK2,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,TGF-b-Smad Signaling Pathway,Protein phosphorylation,LIMK2
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分子量
- 69 kDa/72 kDa/77 kDa
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基因ID
- 3985
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UniProt
- P53671
抗原
-
