CD21 抗体 (FITC)
(2 references)Quick Overview for CD21 抗体 (FITC) (ABIN302019)
抗原
See all CD21 (CR2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD21 FITC
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特异性
- The antibody LT21 reacts with an extracellular epitope of CD21 (CR2), a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
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交叉反应 （详细）
- Human, Porcine, Bovine, Canine (Dog)
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纯化方法
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- IM9 human B-lymphoblastoid cell line
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亚型
- IgG1 kappa
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anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 142-240) antibody
CR2 适用: 人 FACS, IHC, WB, IF, ELISA, StM, Coat 宿主: 小鼠 Monoclonal CR2-2754 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人 FACS, IHC, WB, IF, ELISA 宿主: 兔 Monoclonal 16F10 unconjugated Recombinant Antibody
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 300-590) antibodyCR2 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 740-964) antibodyCR2 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2D2H6 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 981-1092) antibodyCR2 适用: 人, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 142-240) antibodyCR2 适用: 人 FACS, IHC, WB, IF, StM 宿主: 兔 Monoclonal CR2-3124R unconjugated Recombinant Antibody
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) (AA 44-196) antibodyCR2 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal CR2-1952 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, Pig, Cow, 犬 FACS, IHC (fro) 宿主: 小鼠 Monoclonal LT21 unconjugated
anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibodyCR2 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 小鼠 Monoclonal 5F2 unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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溶解方式
- No reconstitution is necessary.
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze.
Avoid prolonged exposure to light. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Fluorescent immunoprecipitation analysis of cell surface proteins: a methodology compatible with mass-spectrometry." in: Journal of immunological methods, Vol. 319, Issue 1-2, pp. 21-33, (2007) (PubMed).
: "Cross-reactive anti-human monoclonal antibodies as a tool for B-cell identification in dogs and pigs." in: Veterinary immunology and immunopathology, Vol. 119, Issue 1-2, pp. 56-62, (2007) (PubMed).
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: "Fluorescent immunoprecipitation analysis of cell surface proteins: a methodology compatible with mass-spectrometry." in: Journal of immunological methods, Vol. 319, Issue 1-2, pp. 21-33, (2007) (PubMed).
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- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
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别名
- CD21
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背景
- Complement C3d receptor 2,CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.,CR2, C3DR2, CVID7, SLEB9
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基因ID
- 1380
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UniProt
- P20023
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途径
- Complement System
抗原
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