CD11c 抗体 (APC)
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北京 101111
Quick Overview for CD11c 抗体 (APC) (ABIN301988)
抗原
See all CD11c (ITGAX) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD11c APC
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交叉反应 （详细）
- Human, Monkey
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产品特性
- The antibody BU15 reacts with an extracellular epitope of CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.
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纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Dendritic cells of synovial fluid
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亚型
- IgG1, kappa
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anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibody
ITGAX 适用: 人, 小鼠, 大鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibody (FITC)ITGAX 适用: 人, 猴 FACS 宿主: 小鼠 Monoclonal BU15 FITC
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 1119-1145) antibodyITGAX 适用: 人 FACS, IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 100-350) antibodyITGAX 适用: 人 IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 637-827) antibodyITGAX 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGAX-1242 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibodyITGAX 适用: 人, 猴 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal BU15 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 102-279) antibodyITGAX 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 6G2D1 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (AA 1119-1145), (C-Term) antibodyITGAX 适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB21771 unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) (N-Term) antibodyITGAX 适用: 人, 小鼠 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) antibody (PerCP)ITGAX 适用: 人, 猴 FACS 宿主: 小鼠 Monoclonal BU15 PerCP
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze,Protect from prolonged exposure to light
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "CD14+ antigen-presenting cells in human dermis are less mature than their CD1a+ counterparts." in: International immunology, Vol. 19, Issue 11, pp. 1271-9, (2007) (PubMed).
: "Regulation of adhesion of AML14.3D10 cells by surface clustering of beta2-integrin caused by ERK-independent activation of cPLA2." in: Immunology, Vol. 107, Issue 1, pp. 77-85, (2002) (PubMed).
: "A novel leukointegrin, alpha d beta 2, binds preferentially to ICAM-3." in: Immunity, Vol. 3, Issue 6, pp. 683-90, (1996) (PubMed).
: "The p150,95 molecule is a marker of human mononuclear phagocytes: comparison with expression of class II molecules." in: European journal of immunology, Vol. 16, Issue 3, pp. 240-8, (1986) (PubMed).
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: "CD14+ antigen-presenting cells in human dermis are less mature than their CD1a+ counterparts." in: International immunology, Vol. 19, Issue 11, pp. 1271-9, (2007) (PubMed).
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- CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
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别名
- CD11c
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背景
- Integrin subunit alpha X,CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.,Integrin alpha X, ITGAX, SLEB6
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基因ID
- 3687
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UniProt
- P20702
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途径
- Complement System, Activated T Cell Proliferation, Integrin Complex
抗原
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