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Mre11 抗体 (AA 1-205)

Name: Mre11 抗体 (AA 1-205)
Brand: antibodies-online
SKU: ABIN3016250
Availability: OutOfStock

This anti-Mre11 antibody is a 兔多克隆 antibody detecting Mre11 in WB, IHC, IP 和 IF. Suitable for 人. This Primary Antibody has been cited in 3+ publications.

Western blot analysis of extracts of various cell lines, using MRE11A antibody. (Mre11 抗体 (AA 1-205))

Immunohistochemistry of paraffin-embedded human esophageal cancer using MRE11 Rabbit pAb (ABIN3016249, ABIN3016250, ABIN3016251 and ABIN6219660) at dilution of 1:50 (40x lens). (Mre11 抗体 (AA 1-205))

IHC

Western blot analysis of extracts of various cell lines, using MRE11 antibody (ABIN3016249, ABIN3016250, ABIN3016251 and ABIN6219660) at 1:1000 dilution. (Mre11 抗体 (AA 1-205))

Immunohistochemistry of paraffin-embedded human colon carcinoma using MRE11 Rabbit pAb (ABIN3016249, ABIN3016250, ABIN3016251 and ABIN6219660) at dilution of 1:50 (40x lens). (Mre11 抗体 (AA 1-205))

IHC

4 images

(3 references)

产品编号 ABIN3016250

发货至: 中国

Quick Overview for Mre11 抗体 (AA 1-205) (ABIN3016250)

抗原

See all Mre11 (MRE11A) 抗体

Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

适用

人

宿主

兔

克隆类型

多克隆

标记

This Mre11 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

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AA 1-205

序列

MSTADALDDE NTFKILVATD IHLGFMEKDA VRGNDTFVTL DEILRLAQEN EVDFILLGGD LFHENKPSRK TLHTCLELLR KYCMGDRPVQ FEILSDQSVN FGFSKFPWVN YQDGNLNISI PVFSIHGNHD DPTGADALCA LDILSCAGFV NHFGRSMSVE KIDISPVLLQ KGSTKIALYG LGSIPDERLY RMFVNKKVTM LRPKE

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human MRE11 (NP_005581.2).

亚型

IgG
anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) antibody
MRE11A 适用: 人, 大鼠, 小鼠, 小鸡, Hamster WB, IHC, IP, IF, ICC, FACS, ChIP 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 451-550) antibody
MRE11A 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-205) antibody
MRE11A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 375-609) antibody
MRE11A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-205) antibody
MRE11A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (C-Term) antibody
MRE11A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (Internal Region) antibody
MRE11A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 2-239) antibody
MRE11A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (AA 1-206) antibody
MRE11A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H4-F4 unconjugated

anti-MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) (Ser916) antibody
MRE11A 适用: 人, 大鼠, 小鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100

限制

仅限研究用
缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Zhang, Chang, Sun, Chen, Yang, Tang, Jing, Kang, He, Wu, Wei, Wang, Xu, Zhu, Shen, Zeng, Wang, Liu, Zhang, Mao, Jiang, Sun: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." in: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).

Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

Zhang, Tang, Jiang, Mao: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
抗原

Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

别名

MRE11

背景

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.,MRE11,ATLD,HNGS1,MRE11A,MRE11B,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,Immunology & Inflammation,MRE11

分子量

77 kDa/80 kDa/81 kDa

基因ID

4361

UniProt

P49959

途径

DNA Damage Repair