ESR2 抗体 (AA 1-280)
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北京 101111
Quick Overview for ESR2 抗体 (AA 1-280) (ABIN3016232)
抗原
See all ESR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-280
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序列
- MDIKNSPSSL NSPSSYNCSQ SILPLEHGSI YIPSSYVDSH HEYPAMTFYS PAVMNYSIPS NVTNLEGGPG RQTTSPNVLW PTPGHLSPLV VHRQLSHLYA EPQKSPWCEA RSLEHTLPVN RETLKRKVSG NRCASPVTGP GSKRDAHFCA VCSDYASGYH YGVWSCEGCK AFFKRSIQGH NDYICPATNQ CTIDKNRRKS CQACRLRKCY EVGMVKCGSR RERCGYRLVR RQRSADEQLH CAGKAKRSGG HAPRVRELLL DALSPEQLVL TLLEAEPPHV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human Estrogen Receptor beta (NP_001201832.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ESR2 (Estrogen Receptor 2 (ESR2))
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别名
- ESR2
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背景
- This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.,ESR2,ER-BETA,ESR-BETA,ESRB,ESTRB,Erb,NR3A2,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Tumor biomarkers,Signal Transduction,MAPK-Erk Signaling Pathway,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Neuroscience,ESR2
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分子量
- 35-59 kDa
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基因ID
- 2100
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UniProt
- Q92731
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途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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