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GPX4 抗体 (AA 30-197)

Name: GPX4 抗体 (AA 30-197)
Brand: antibodies-online
SKU: ABIN3015730
Availability: OutOfStock

This anti-GPX4 antibody is a 兔多克隆 antibody detecting GPX4 in WB, IHC, IF 和 IP. Suitable for 人. This Primary Antibody has been cited in 1 publication.

Western Blotting (WB) image for anti-Glutathione Peroxidase 4 (GPX4) (AA 30-197) antibody (ABIN3015730) (GPX4 抗体 (AA 30-197))

Immunofluorescence analysis of U2OS cells using GPX4 Rabbit pAb (ABIN3015729, ABIN3015730, ABIN3015731, ABIN1680090 and ABIN6219078) at dilution of 1:200 (40x lens). (GPX4 抗体 (AA 30-197))

Immunofluorescence analysis of A549 cell using GPX4 antibody. (GPX4 抗体 (AA 30-197))

Immunohistochemistry (IHC) image for anti-Glutathione Peroxidase 4 (GPX4) (AA 30-197) antibody (ABIN3015730) (GPX4 抗体 (AA 30-197))

IHC

Western blot analysis of extracts of various cell lines, using GPX4 antibody (ABIN3015729, ABIN3015730, ABIN3015731, ABIN1680090 and ABIN6219078) at 1:1000 dilution. (GPX4 抗体 (AA 30-197))

Immunofluorescence analysis of C6 cells using GPX4 Rabbit pAb (ABIN3015729, ABIN3015730, ABIN3015731, ABIN1680090 and ABIN6219078) at dilution of 1:200 (40x lens). (GPX4 抗体 (AA 30-197))

Immunofluorescence analysis of A-549 cells using GPX4 Rabbit pAb (ABIN3015729, ABIN3015730, ABIN3015731, ABIN1680090 and ABIN6219078) at dilution of 1:200 (40x lens). (GPX4 抗体 (AA 30-197))

Immunofluorescence analysis of NIH/3T3 cells using GPX4 Rabbit pAb (ABIN3015729, ABIN3015730, ABIN3015731, ABIN1680090 and ABIN6219078) at dilution of 1:200 (40x lens). (GPX4 抗体 (AA 30-197))

8 images

(1 reference)

产品编号 ABIN3015730

发货至: 中国

Datasheet as PDF

Quick Overview for GPX4 抗体 (AA 30-197) (ABIN3015730)

抗原

See all GPX4 抗体

GPX4 (Glutathione Peroxidase 4 (GPX4))

适用

人

宿主

兔

克隆类型

多克隆

标记

This GPX4 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

抗原表位
11

4

3

2

1

1

1

1

1
AA 30-197

序列

ASRDDWRCAR SMHEFSAKDI DGHMVNLDKY RGFVCIVTNV ASQUGKTEVN YTQLVDLHAR YAECGLRILA FPCNQFGKQE PGSNEEIKEF AAGYNVKFDM FSKICVNGDD AHPLWKWMKI QPKGKGILGN AIKWNFTKFL IDKNGCVVKR YGPMEEPLVI EKDLPHYF

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 30-197 of human GPX4 (NP_002076.2).

亚型

IgG
anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibody
GPX4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibody
GPX4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (C-Term) antibody
GPX4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (C-Term) antibody
Verified GPX4 适用: 人 WB, IHC, ELISA, IP 宿主: 山羊 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) antibody
KO Validated GPX4 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibody
GPX4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (AA 72-121) antibody
GPX4 适用: 人, 小鼠, 大鼠, 斑马鱼, 豚鼠, Cow, 猴, 山羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) (AA 81-93) antibody
GPX4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) antibody
GPX4 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Glutathione Peroxidase 4 (GPX4) antibody
GPX4 适用: 人, 小鼠, 大鼠 IHC, ELISA, IF, FACS, Coat, StM 宿主: 小鼠 Monoclonal LHM 2 unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

限制

仅限研究用
缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Wang, Zheng, Zhang, Zhao, Wang, Wang, Shang, Barasch, Qiu: "Physiological functions of ferroportin in the regulation of renal iron recycling and ischemic acute kidney injury." in: American journal of physiology. Renal physiology, Vol. 315, Issue 4, pp. F1042-F1057, (2018) (PubMed).
抗原

GPX4 (Glutathione Peroxidase 4 (GPX4))

别名

GPX4

背景

The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death. It is also required for normal sperm development, thus, it has been identified as a 'moonlighting' protein because of its ability to serve dual functions as a peroxidase, as well as a structural protein in mature spermatozoa. Mutations in this gene are associated with Sedaghatian type of spondylometaphyseal dysplasia (SMDS). This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.,GPX4,GPx-4,GSHPx-4,MCSP,PHGPx,SMDS,snGPx,snPHGPx,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,GPX4

分子量

19 kDa/22 kDa

基因ID

2879

UniProt

P36969