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PITX2 抗体 (AA 1-100)

This anti-PITX2 antibody is a 兔 多克隆 antibody detecting PITX2 in WB. Suitable for 人.
产品编号 ABIN3015652
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PITX2 抗体 (AA 1-100) (ABIN3015652)

抗原

See all PITX2 抗体
PITX2 (Paired-Like Homeodomain 2 (PITX2))

适用

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宿主

  • 42
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克隆类型

  • 45
  • 6
多克隆

标记

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This PITX2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-100

    序列

    MNCMKGPLHL EHRAAGTKLS AVSSSSCHHP QPLAMASVLA PGQPRSLDSS KHRLEVHTIS DTSSPEAAEK DKSQQGKNED VGAEDPSKKK RQRRQRTHFT

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PITX2 (NP_000316.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PITX2 (Paired-Like Homeodomain 2 (PITX2))

    别名

    PITX2

    背景

    This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.,PITX2,ARP1,ASGD4,Brx1,IDG2,IGDS,IGDS2,IHG2,IRID2,Otlx2,PTX2,RGS,RIEG,RIEG1,RS,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Cardiovascular,Heart,Cardiogenesis,PITX2

    分子量

    30 kDa/35 kDa

    基因ID

    5308

    UniProt

    Q99697

    途径

    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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