IKZF1 抗体 (C-Term)
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北京 101111
Quick Overview for IKZF1 抗体 (C-Term) (ABIN2967181)
抗原
See all IKZF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Anti-Ikaros Purified
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交叉反应 (详细)
- Human, Mouse
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产品特性
- The mouse monoclonal antibody 4E9 recognizes Ikaros, a transcription factor (intracellular antigen) expressed broadly in hematopoietic progenitors and serving as a key regulator of lymphopoiesis.
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Recombinant human Ikaros (C-terminal part)
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亚型
- IgG1
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
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别名
- Ikaros
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背景
- IKAROS family zinc finger 1,Ikaros, also known as IKZF1 (Ikaros family zinc finger protein 1) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Helios. Ikaros forms homo- and heterodimers with these proteins and functions predominantly in early hematopoietic development. Expression of Ikaros, Aiolos and Helios is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Disruption of Ikaros leads to T and B cell leukemias.,IKZF1, IK1, LYF1, LyF-1, IKAROS, PPP1R92, PRO0758, ZNFN1A1, Hs.54452, IKAROS family zinc finger 1, Lymphoid transcription factor LyF-1
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基因ID
- 10320
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UniProt
- Q13422
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途径
- Production of Molecular Mediator of Immune Response
抗原
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