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CSF3R 抗体 (PE)

This anti-CSF3R antibody is a 小鼠 单克隆 antibody detecting CSF3R in FACS. Suitable for 人.
产品编号 ABIN2967164
发货至: 中国

Quick Overview for CSF3R 抗体 (PE) (ABIN2967164)

抗原

See all CSF3R 抗体
CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CSF3R antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

LMM741
  • 原理

    Anti-Hu CD114 PE

    特异性

    The mouse monoclonal antibody LMM741 recognizes an extracellular epitope of CD114 (colony stimulating factor 3 receptor), a 130 kDa transmembrane glycoprotein expressed on granulocytes and their differentiation stages, on monocytes, platelets, endothelial cells and placenta. It is absent from lymphocytes and erythrocytes.

    无交叉反应

    小鼠

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    CHO cells transfected with human CD114

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

    别名

    CD114

    背景

    Colony stimulating factor 3 receptor,CD114 / G-CSFR (granulocyte colony-stimulating factor receptor, also known as CSF3R) is a type I transmembrane glycoprotein which upon binding of its ligand (G-CSF, granulocyte colony-stimulating factor) homodimerizes and activates signaling transduction to mediate cell proliferation, survival, and differentiation. It is expressed by granulocytes at all stages of their differentiation, as well as by monocytes, dendritic cells, and mature platelets. Among non-hematopoietic cells, it is expressed e.g. by endothelial cells, placenta, trophoblasts, and many tumor cell lines. This antigen is a target for stem cell mobilization for blood stem cell transplantation, for enhancing recovery of myelopoiesis following chemotherapy and in the treatment of patients with severe chronic neutropenia.,GCSFR, CSF3R, SCN7

    基因ID

    1441

    UniProt

    Q99062
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