FKBP4 抗体 (full length, N-Term)
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- 抗原 See all FKBP4 抗体
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
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抗原表位
- full length, N-Term
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适用
- 人, 小鼠, 大鼠, Hamster, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FKBP4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 特异性
- Reacts with human FKBP52. Cross-reacts with mouse, rat, canine and hamster protein.
- 纯化方法
- Purified (protein G)
- 免疫原
- Recombinant full-length FKBP52 with an N-terminal polyhistidine tag.
- 克隆位点
- Hi52C
- 亚型
- IgG1
- Top Product
- Discover our top product FKBP4 Primary Antibody
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anti-FK506 Binding Protein 4, 59kDa (FKBP4) (AA 301-410) antibody
FKBP4 适用: 人 WB, IP, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5C11 unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) (AA 2-459) antibodyFKBP4 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) antibodyFKBP4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) antibodyFKBP4 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) (AA 220-459) antibodyFKBP4 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) antibodyFKBP4 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal Hi52C unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) antibodyFKBP4 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 4, 59kDa (FKBP4) antibody (HRP)FKBP4 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal Hi52C HRP
anti-FK506 Binding Protein 4, 59kDa (FKBP4) antibody (FITC)FKBP4 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal Hi52C FITC
anti-FK506 Binding Protein 4, 59kDa (FKBP4) antibody (Alkaline Phosphatase (AP))FKBP4 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal Hi52C Alkaline Phosphatase (AP)
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- 应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
FC(1-2 μg for 10.6 cells) IHC(4 - 5 μg/mL) WB(0.5 - 1 μg/mL)
Positive control: HeLa cell lysate, rat kidney and rat/mouse testes tissue. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, glycerol 50 % .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Dilute in PBS or medium that is identical to that used in the assay system.
- 储存条件
- -20 °C
- 储存方法
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
- 别名
- FKBP52 (FKBP4 产品)
- 别名
- HBI antibody, p52 antibody, hsp56 antibody, PPIase antibody, fkbp52 antibody, fkbp59 antibody, MGC81078 antibody, wu:fb34f09 antibody, 59kDa antibody, AL022792 antibody, AW208983 antibody, FKBP-4 antibody, FKBP-52 antibody, FKBP52 antibody, FKPB52 antibody, p59 antibody, FKBP51 antibody, FKBP59 antibody, Hsp56 antibody, P59 antibody, FK506 binding protein 4 antibody, FK506 binding protein 4 S homeolog antibody, FKBP4 antibody, fkbp4.S antibody, fkbp4 antibody, Fkbp4 antibody
- 背景
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FK506-binding proteins, FKBP51 and FKBP52, are high molecular weight immunophilins that are part of the mature glucocorticoid receptor heterocomplex. The N-terminal domains of these proteins bind FK506 and have peptidyl-prolyl isomerase activity that converts prolyl peptide bonds within target proteins from cis- to transproline. The C-terminal domains contain the tetratricopeptide repeats that are involved in protein-protein interactions with Hsp90. Although FKBP52 and FKBP51 share ~75 % sequence similarity, they affect hormone binding by glucocorticoid receptors differently and have different Hsp90-binding characteristics. In addition, FKBP51 is linked to the progesterone receptor while FKBP52 is linked to progesterone, androgen, and glucocorticoid receptors.
Peptidyl-prolyl cis-trans isomerase FKBP4, PPIase FKBP4 51 kDa FK506-binding protein, FKBP51 52 kDa FK506-binding protein, FKBP-52 59 kDa immunophilin, p59 FK506-binding protein 4, FKBP-4 FKBP59 HSP-binding immunophilin, HBI Immunophilin FKBP52 Rotamase Gene name : FKBP4 - 基因ID
- 2288
- UniProt
- Q02790
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
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