Mannose Receptor 抗体
Quick Overview for Mannose Receptor 抗体 (ABIN291690)
抗原
See all Mannose Receptor (MR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Specific for human CD206, otherwise known as macrophage mannose receptor (MMR), a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens. CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and adaptive immunity, with CD206 able to bind to both gram-negative and gram-positive bacteria, mycobacterium, yeasts, fungi and parasites.
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纯化方法
- Affinity purified
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免疫原
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Monocyte-derived dendritic cells.
Type of Immunogen: Cells -
亚型
- IgG2a
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anti-Mannose Receptor (MR) antibody
MR 适用: 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor (MR) (AA 359-388) antibodyMR 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor (MR) (AA 22-131) antibodyMR 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5C11 unconjugated
anti-Mannose Receptor (MR) antibodyMR 适用: 人 FACS, WB, IHC, IHC (fro) 宿主: 小鼠 Monoclonal 15-2 unconjugated
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应用备注
- Approved: IHC, IHC-Fr (1:50 - 1:500)
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Short term: -20°C
Long term: -20°C.
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- Mannose Receptor (MR)
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别名
- Mannose Receptor / CD206
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背景
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Name/Gene ID: MRC1
Synonyms: MRC1, BA541I19.1, CLEC13D, CD206, CD206 antigen, Macrophage mannose receptor 1, Mannose Receptor, Macrophage mannose receptor, MMR, Mannose receptor, C type 1, MRC1L1, CLEC13DL -
基因ID
- 4360
抗原
-
