MICA/B 抗体
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北京 101111
Quick Overview for MICA/B 抗体 (ABIN291612)
抗原
适用
宿主
克隆类型
标记
应用范围
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特异性
- Specific for nonclassical MHC class I chain A (MICA) and nonclassical MHC class I chain MICB (MICB). MICA and MICB are stress inducible antigens, which are closely related and appear functionally indistinguishable. MICA and MICB are ligands for NKG2D, an activating receptor on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. MICA is principally expressed on intestinal epithelium, and several epithelial tumors. Expression may be induced to high surface levels by heat shock, oxidative stress, and virus infection. Clone 6D4 is reported to inhibit the cytotoxicity of NK cells stimulated by IFN alpha-treated dendritic cells. XXX recommend the use of MCA2304EL for such studies.
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纯化方法
- Protein G purified
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免疫原
- MICA transfected C1R cells.
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亚型
- IgG2a
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anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) antibody
MICA/MICB 适用: 人 FACS, IP, IHC 宿主: 小鼠 Monoclonal 6D4 unconjugated
anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) (AA 81-180) antibodyMICA/MICB 适用: 人 IF (cc), IF (p), IHC (fro), ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) antibody (Biotin)MICA/MICB 适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal 6D4 Biotin
anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) antibody (FITC)MICA/MICB 适用: 人 FACS 宿主: 小鼠 Monoclonal 6D4 FITC
anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) antibody (APC)MICA/MICB 适用: 人 FACS 宿主: 小鼠 Monoclonal 6D4 APC
anti-MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB) antibody (PE)MICA/MICB 适用: 人 FACS 宿主: 小鼠 Monoclonal 6D4 PE
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应用备注
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Approved: Flo, IHC, IHC-Fr (1:100), IP
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. Membrane permeabilization is required for this application. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- MICA/B (MICA/MICB) (MHC Class I Polypeptide-Related Sequence A/B (MICA/MICB))
抗原
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