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UCP2 抗体

UCP2 适用: 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN289564
发货至: 中国
  • 抗原 See all UCP2 抗体
    UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
    适用
    • 71
    • 58
    • 42
    小鼠
    宿主
    • 73
    • 7
    • 1
    • 1
    克隆类型
    • 77
    • 5
    多克隆
    标记
    • 27
    • 12
    • 5
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    • 3
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    • 3
    • 3
    • 3
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    This UCP2 antibody is un-conjugated
    应用范围
    • 75
    • 39
    • 39
    • 18
    • 18
    • 17
    • 10
    • 9
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    • 5
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    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    特异性
    This antibody reacts with residues 125-142 EETAKKVRRAIEQLAAMD of the human Survivin protein. Cross reacts with mouse and rat Survivin (88% sequenceidentity).
    交叉反应 (详细)
    This UCP2 peptide sequence is 100 % conserved in rat, hamster, and 86 % in human, pig, canine, and bovine UCP2. It has no significant homology with UCP1, UCP3-5.
    纯化方法
    Affinity chromatography purified
    免疫原
    UCP2 antibody was raised in rabbit using a 14 amino acid peptide from mouse UCP2 as the immunogen.
    亚型
    IgG
    Top Product
    Discover our top product UCP2 Primary Antibody
  • 应用备注
    ELISA: 1:10,000-1:100,000, HC: 2-20 µg/mL, IF: 2-20 µg/mL, WB: 1-10 µg/mL
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in PBS to a concentraiton of 1 mg/mL.
    浓度
    Lot specific
    缓冲液
    Affinity purified antibody lyophilized from PBS with 0.1 % BSA.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • 抗原
    UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
    别名
    UCP2 (UCP2 产品)
    别名
    UCP2 antibody, DKFZp470P1633 antibody, ucp2 antibody, MGC53319 antibody, MGC75881 antibody, cb74 antibody, ATUCP2 antibody, K19M22.21 antibody, K19M22_21 antibody, uncoupling protein 2 antibody, BMIQ4 antibody, SLC25A8 antibody, UCPH antibody, Slc25a8 antibody, mitochondrial uncoupling protein 2 antibody, uncoupling protein 2 antibody, uncoupling protein 2 (mitochondrial, proton carrier) L homeolog antibody, uncoupling protein 2 (mitochondrial, proton carrier) antibody, uncoupling protein 1 antibody, PTRG_09289 antibody, UCP2 antibody, LOC100282746 antibody, ucp2.L antibody, ucp2 antibody, ucp1 antibody, Ucp2 antibody
    背景
    Uncoupling proteins (UCP1-5) are a family of mitochondria transport proteins that play a critical role in thermoregulatory heat production and maintenance of basal metabolic rate. UCP3 is predicted to contain 6 transmembrane domains. The UCP3S lacks the 6th transmembrane domain and it is only 275 aa long. Mouse/rat UCP2 is A 309 AA (human 309 aa chromosome 7, ~95% homology) mitochondrial uncoupling protein. UCP2 has wide tissue distribution in mouse tissues (brain, kidney, liver, brown adipose tissue, heart, and muscle). UCP2 may play a critical role in energy balance, body weight, and thermoregulation.
    途径
    Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Proton Transport
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