LYVE1 抗体
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北京 101111
Quick Overview for LYVE1 抗体 (ABIN289493)
抗原
See all LYVE1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Protein A affinity chromatography
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免疫原
- LYVE1 antibody was raised in rabbit using recombinant mouse soluble Lyve-1 as the immunogen.
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亚型
- IgG
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应用备注
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ELISA: 1-15 µg/mL, FC: 3-10 µg/mL, WB:2-5 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Supplied in lyophilized formin PBS buffer
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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: "Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration." in: Cell reports, Vol. 30, Issue 4, pp. 1052-1062.e5, (2020) (PubMed).
: "Tissue-engineered 3D melanoma model with blood and lymphatic capillaries for drug development." in: Scientific reports, Vol. 8, Issue 1, pp. 13191, (2019) (PubMed).
: "Regulation of T cell afferent lymphatic migration by targeting LTβR-mediated non-classical NFκB signaling." in: Nature communications, Vol. 9, Issue 1, pp. 3020, (2018) (PubMed).
: "Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination." in: Nature communications, Vol. 7, pp. 10634, (2016) (PubMed).
: "Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration." in: Nature communications, Vol. 7, pp. 12021, (2016) (PubMed).
: "RASA3 is a critical inhibitor of RAP1-dependent platelet activation." in: The Journal of clinical investigation, Vol. 125, Issue 4, pp. 1419-32, (2015) (PubMed).
: "Inhibition of BMP signaling suppresses metastasis in mammary cancer." in: Oncogene, Vol. 34, Issue 19, pp. 2437-49, (2015) (PubMed).
: "Identification of lymphatics in the ciliary body of the human eye: a novel "uveolymphatic" outflow pathway." in: Experimental eye research, Vol. 89, Issue 5, pp. 810-9, (2009) (PubMed).
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: "Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration." in: Cell reports, Vol. 30, Issue 4, pp. 1052-1062.e5, (2020) (PubMed).
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- LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
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别名
- LYVE1
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背景
- LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily.
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途径
- Glycosaminoglycan Metabolic Process
抗原
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