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LYVE1 抗体

There are 8+ publications for this product available. The 兔 多克隆 anti-LYVE1 antibody is suitable to detect LYVE1 in samples from 小鼠. It has been validated for WB, ELISA 和 FACS.
产品编号 ABIN289493
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LYVE1 抗体 (ABIN289493)

抗原

See all LYVE1 抗体
LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This LYVE1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 纯化方法

    Protein A affinity chromatography

    免疫原

    LYVE1 antibody was raised in rabbit using recombinant mouse soluble Lyve-1 as the immunogen.

    亚型

    IgG
  • 应用备注

    ELISA: 1-15 µg/mL, FC: 3-10 µg/mL, WB:2-5 µg/mL
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Supplied in lyophilized formin PBS buffer

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • Piao, Xiong, Li, Saxena, Smith, Hippen, Paluskievicz, Willsonshirkey, Blazar, Abdi, Bromberg: "Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration." in: Cell reports, Vol. 30, Issue 4, pp. 1052-1062.e5, (2020) (PubMed).

    Bourland, Fradette, Auger: "Tissue-engineered 3D melanoma model with blood and lymphatic capillaries for drug development." in: Scientific reports, Vol. 8, Issue 1, pp. 13191, (2019) (PubMed).

    Piao, Xiong, Famulski, Brinkman, Li, Toney, Wagner, Saxena, Simon, Bromberg: "Regulation of T cell afferent lymphatic migration by targeting LTβR-mediated non-classical NFκB signaling." in: Nature communications, Vol. 9, Issue 1, pp. 3020, (2018) (PubMed).

    Le, Nowell, Kim-Fuchs, Botteri, Hiller, Ismail, Pimentel, Chai, Karnezis, Rotmensz, Renne, Gandini, Pouton, Ferrari, Möller, Stacker, Sloan: "Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination." in: Nature communications, Vol. 7, pp. 10634, (2016) (PubMed).

    Brinkman, Iwami, Hritzo, Xiong, Ahmad, Simon, Hippen, Blazar, Bromberg: "Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration." in: Nature communications, Vol. 7, pp. 12021, (2016) (PubMed).

    Stefanini, Paul, Robledo, Chan, Getz, Campbell, Kechele, Casari, Piatt, Caron, Mackman, Weyrich, Parrott, Boulaftali, Adams, Peters, Bergmeier: "RASA3 is a critical inhibitor of RAP1-dependent platelet activation." in: The Journal of clinical investigation, Vol. 125, Issue 4, pp. 1419-32, (2015) (PubMed).

    Owens, Pickup, Novitskiy, Giltnane, Gorska, Hopkins, Hong, Moses: "Inhibition of BMP signaling suppresses metastasis in mammary cancer." in: Oncogene, Vol. 34, Issue 19, pp. 2437-49, (2015) (PubMed).

    Yücel, Johnston, Ly, Patel, Drake, Gümüş, Fraenkl, Moore, Tobbia, Armstrong, Horvath, Gupta: "Identification of lymphatics in the ciliary body of the human eye: a novel "uveolymphatic" outflow pathway." in: Experimental eye research, Vol. 89, Issue 5, pp. 810-9, (2009) (PubMed).

  • 抗原

    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

    别名

    LYVE1

    背景

    LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily.

    途径

    Glycosaminoglycan Metabolic Process
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