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IL-13 抗体

IL13 适用: 人 WB, ELISA, Inhibition 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN289477
发货至: 中国
  • 抗原 See all IL-13 (IL13) 抗体
    IL-13 (IL13) (Interleukin 13 (IL13))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This IL-13 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
    纯化方法
    Affinity chromatography purified
    免疫原
    IL13 antibody was raised in rabbit using highly pure recombinant human IL-13 as the immunogen.
    Top Product
    Discover our top product IL13 Primary Antibody
  • 应用备注
    ELISA: 0.5-2 µg/mL, Inhibition: 0.12-0.15 µg/mL, WB: 0.1-0.2 µg/mL
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized from 0.5 x PBS, pH 7.4.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • 抗原
    IL-13 (IL13) (Interleukin 13 (IL13))
    别名
    IL13 (IL13 产品)
    别名
    IL13 antibody, IL-13 antibody, P600 antibody, Il-13 antibody, L13 antibody, interleukin 13 antibody, IL13 antibody, Il13 antibody
    背景
    IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL13 in mice resulted in impaired Th2 cell development and indicated an important role for IL13 in the expulsion of gastrointestinal parasites. IL13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL1beta, TNF-alpha, IL6 and IL8. IL13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL13 activity inhibits the pathophysiology of asthma. Human and Mouse IL13 is cross-species reactive.
    分子量
    12.3 kDa (predicted detection band MW)
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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