UVRAG 抗体 (Biotin)
Quick Overview for UVRAG 抗体 (Biotin) (ABIN2868821)
抗原
See all UVRAG 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Predicted molecular weight at ~78.1 kDa. Observed molecular weights in the 75-90 kDa range.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Peptide Affinity Purified
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免疫原
- Synthetic peptide from the mid-protein of human UVRAG
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应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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A 1:1000 dilution of ABIN2868821 was sufficient for detection of UVRAG on HeLa cell lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
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别名
- UVRAG
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背景
- UVRAG (UV radiation resistance-associated gene) is associated with the Beclin-1/PI3KC3 complex and promotes PI3KC3 enzymatic activity and autophagy, while suppressing proliferation (1). Beclin-1 binding to UVRAG promotes both autophagosome maturation and endocytic trafficking (2). UVRAG is also a potential tumor suppressor protein with frameshift mutations observed in colon and gastric carcinomas (3-4). It is highly expressed in the brain, lung, kidney and liver.
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基因ID
- 7405
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NCBI登录号
- NP_003360
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UniProt
- Q9P2Y5
抗原
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