RAGE 抗体
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北京 101111
Quick Overview for RAGE 抗体 (ABIN285943)
抗原
See all RAGE (AGER) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Specific for Amino acid sequence 385-399 of human receptor for advanced glycated end products.0.1% NaN3
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免疫原
- RAGE antibody was raised in goat using a peptide, PKKPPQRLEWKLNTGRTE, as the immunogen.
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应用备注
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ELISA: >1:260,676, IHC-P: >1:400, WB: >1:3,000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Supplied as liquid whole serum without preservative
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
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别名
- RAGE
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背景
- The Receptor for Advanced Glycosylated End Products (RAGE) is a member of the immunoglobulin superfamily of cell surface molecules that binds molecules that have been irreversibly modified by non-enzymatic glycation and oxidation, and are know as advanced glycation end products (AGEs). It is expressed by endothelium, mononuclear phagocytes, neurons and smooth muscle cells. Whereas RAGE is present at high levels during development, especially in the central nervous system, its levels decline during maturity.
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途径
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
抗原
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