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Perforin 1 抗体

The 兔 多克隆 anti-Perforin 1 antibody (ABIN285909) specifically detects Perforin 1 in WB. The antibody is reactive with 大鼠 samples.
产品编号 ABIN285909
发货至: 中国
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Quick Overview for Perforin 1 抗体 (ABIN285909)

抗原

See all Perforin 1 (PRF1) 抗体
Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

适用

  • 124
  • 32
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  • 1
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  • 1
大鼠

宿主

  • 77
  • 65
  • 8

克隆类型

  • 93
  • 57
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
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This Perforin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 交叉反应

    小鼠, 大鼠

    交叉反应 (详细)

    Reacts with both rat and mouse perforin. Cross-reactivity to perforin of other species has not been tested.

    纯化方法

    purified

    免疫原

    Perforin antibody was raised in rabbit using E. coli-expressed rat perforin as the immunogen.
  • 应用备注

    WB: 1:1,000
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitue in distilled water.

    浓度

    Lot specific

    缓冲液

    Supplied as a lyophilized Potein A purified rabbit IgG with 0.1 % NaN3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • 抗原

    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

    别名

    Perforin

    背景

    Perforin-1 is a protein that in humans is encoded by the PRF1 gene. Perforin is a cytolytic protein found in the granules of CD8 T-cells and NK cells. Upon degranulation, perforin inserts itself into the target cell's plasma membrane, forming a pore. The lytic membrane-inserting part of perforin is the MACPF domain. This region shares homology with cholesterol-dependent cytolysins from Gram-positive bacteria.

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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