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8-OHDG 抗体

This anti-8-OHDG antibody is a 山羊 多克隆 antibody detecting 8-OHDG in ELISA 和 IHC. Suitable for . This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN285804
发货至: 中国

Quick Overview for 8-OHDG 抗体 (ABIN285804)

抗原

8-OHDG (8-Hydroxyguanosine (8-OHDG))

宿主

  • 9
  • 1
山羊

克隆类型

  • 9
  • 1
多克隆

标记

  • 10
This 8-OHDG antibody is un-conjugated

应用范围

  • 7
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • 免疫原

    8-Hydroxyguanosine antibody was raised in goat using 8-Hydroxyguansoine as the immunogen.
  • 应用备注

    ELISA: >1:250,000, IHC-P: >1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Supplied as liquid whole serum without preservative

    储存液

    Without preservative

    注意事项

    Avoid repeated freeze/thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • Tuerdi, Kikuta, Kinoshita, Kamogashira, Kondo, Yamasoba: "Zone-specific damage of the olfactory epithelium under protein restriction." in: Scientific reports, Vol. 10, Issue 1, pp. 22175, (2021) (PubMed).

    Jeannot, Pogribny, Beland, Rusyn: "Chronic administration of ethanol leads to an increased incidence of hepatocellular adenoma by promoting H-ras-mutated cells." in: Cancer letters, Vol. 301, Issue 2, pp. 161-7, (2011) (PubMed).

  • 抗原

    8-OHDG (8-Hydroxyguanosine (8-OHDG))

    物质类

    Chemical

    背景

    8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually leads to several diseases in humans, such as arteriosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer?s disease.
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