Smooth Muscle Actin 抗体 (N-Term)
(9 references)Quick Overview for Smooth Muscle Actin 抗体 (N-Term) (ABIN2857027)
抗原
See all Smooth Muscle Actin (ACTA2) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- N-Term
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交叉反应
- 人, 小鼠, 大鼠, 斑马鱼
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产品特性
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Rabbit polyclonal antibody to alpha Smooth Muscle Actin
alpha Smooth Muscle Actin antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human alpha Smooth Muscle Actin. The exact sequence is proprietary.
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亚型
- IgG
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anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) (N-Term) antibody
Verified ACTA2 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) (N-Term) antibodyACTA2 适用: 人, 大鼠, 小鼠, Cow WB, IHC, IF, ELISA, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) (N-Term) antibodyACTA2 适用: 人, 大鼠 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal 1A4-ACTA2-791 unconjugated
anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) (AA 1-124) antibodyACTA2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) (AA 2-124) antibodyACTA2 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 5C1H11 unconjugated
anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) (AA 167-377) antibodyACTA2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) antibodyACTA2 适用: 人, 大鼠, 小鼠, 小鸡, 兔, 山羊 WB, IHC, ELISA, IHC (p), ICC, IHC (fro), IEM 宿主: 小鼠 Monoclonal alpha-SM1-1A4 unconjugated
anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) (AA 1-377) antibodyACTA2 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 4A8-2H3 unconjugated
anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) antibodyACTA2 适用: 人, 猴 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4F4 unconjugated
anti-Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) antibodyACTA2 适用: 人, 大鼠, 小鼠, 猴 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 1H8 unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Rat2 , C8D30 , NIH-3T3 , C2C12
Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.37 mg/mL
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缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Therapeutic Targeting of Aristolochic Acid Induced Uremic Toxin Retention, SMAD 2/3 and JNK/ERK Pathways in Tubulointerstitial Fibrosis: Nephroprotective Role of Propolis in Chronic Kidney Disease." in: Toxins, Vol. 12, Issue 6, (2020) (PubMed).
: "Nephrotoxic Effects in Zebrafish after Prolonged Exposure to Aristolochic Acid." in: Toxins, Vol. 12, Issue 4, (2020) (PubMed).
: "SOX18 Affects Cell Viability, Migration, Invasiveness, and Apoptosis in Hepatocellular Carcinoma (HCC) Cells by Participating in Epithelial-to-Mesenchymal Transition (EMT) Progression and Adenosine ..." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 25, pp. 6244-6254, (2020) (PubMed).
: "Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium." in: Developmental cell, Vol. 50, Issue 2, pp. 247-255.e3, (2020) (PubMed).
: "The Bioactive Core and Corona Synergism of Quantized Gold Enables Slowed Inflammation and Increased Tissue Regeneration in Wound Hypoxia." in: International journal of molecular sciences, Vol. 21, Issue 5, (2020) (PubMed).
: "Connective tissue growth factor mediates transforming growth factor β-induced collagen expression in human endometrial stromal cells." in: PLoS ONE, Vol. 14, Issue 1, pp. e0210765, (2019) (PubMed).
: "Guidance to rational use of pharmaceuticals in gallbladder sarcomatoid carcinoma using patient-derived cancer cells and whole exome sequencing." in: Oncotarget, Vol. 8, Issue 3, pp. 5349-5360, (2018) (PubMed).
: "Collagen XII Contributes to Epicardial and Connective Tissues in the Zebrafish Heart during Ontogenesis and Regeneration." in: PLoS ONE, Vol. 11, Issue 10, pp. e0165497, (2017) (PubMed).
: "Modelling human development and disease in pluripotent stem-cell-derived gastric organoids." in: Nature, Vol. 516, Issue 7531, pp. 400-4, (2014) (PubMed).
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: "Therapeutic Targeting of Aristolochic Acid Induced Uremic Toxin Retention, SMAD 2/3 and JNK/ERK Pathways in Tubulointerstitial Fibrosis: Nephroprotective Role of Propolis in Chronic Kidney Disease." in: Toxins, Vol. 12, Issue 6, (2020) (PubMed).
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- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
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别名
- actin alpha 2, smooth muscle
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背景
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The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
Cellular Localization: Cytoplasm , cytoskeleton -
分子量
- 42 kDa
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基因ID
- 59
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UniProt
- P62736
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途径
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
抗原
-
