RORA 抗体
(2 references)Quick Overview for RORA 抗体 (ABIN2857022)
抗原
See all RORA 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Rabbit Polyclonal antibody to ROR alpha (RAR-related orphan receptor A)
ROR alpha antibody [N2N3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ROR alpha. The exact sequence is proprietary.
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亚型
- IgG
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anti-RAR-Related Orphan Receptor A (RORA) (Middle Region) antibody
RORA 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 山羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor A (RORA) (Hinge Region) antibodyRORA 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 猴, Pig, Bat, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor A (RORA) (N-Term) antibodyRORA 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor A (RORA) (AA 193-222) antibodyRORA 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB16632 unconjugated
anti-RAR-Related Orphan Receptor A (RORA) antibodyRORA 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor A (RORA) (AA 164-401) antibodyRORA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor A (RORA) (AA 36-85) antibodyRORA 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor A (RORA) (Ligand Binding Domain) antibodyRORA 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 猴, Pig, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor A (RORA) (AA 1-468) antibodyRORA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor A (RORA) (AA 239-288) antibodyRORA 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 猴, 山羊, Pig, 斑马鱼, Bat, 绵羊, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Mouse brain , HeLa , NIH-3T3
Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling." in: Nature communications, Vol. 10, Issue 1, pp. 2571, (2019) (PubMed).
: "RORα and RORγ expression inversely correlates with human melanoma progression." in: Oncotarget, Vol. 7, Issue 39, pp. 63261-63282, (2018) (PubMed).
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: "LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling." in: Nature communications, Vol. 10, Issue 1, pp. 2571, (2019) (PubMed).
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- RORA (RAR-Related Orphan Receptor A (RORA))
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别名
- RAR related orphan receptor A
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背景
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The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
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分子量
- 63 kDa
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基因ID
- 6095
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UniProt
- P35398
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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