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CXCR7 抗体

Name: CXCR7 抗体
Brand: antibodies-online
SKU: ABIN2857021
Availability: OutOfStock

This anti-CXCR7 antibody is a 兔多克隆 antibody detecting CXCR7 in WB, ELISA, FACS, IF, IHC (p), IP, ICC 和 IHC (fro). Suitable for 人. This Primary Antibody has been cited in 7+ publications.

WB Image Sample (30 ug of whole cell lysate) A: PC-3 B: U87-MG 10% SDS PAGE antibody diluted at 1:1000 (CXCR7 抗体)

IHC-P Image Immunohistochemical analysis of paraffin-embedded Human pancreatic tumor, using CXCR7, antibody at 1:100 dilution. (CXCR7 抗体)

IHC

IHC-P Image Immunohistochemical analysis of paraffin-embedded human gastric cancer, using CXCR7, antibody at 1:100 dilution. (CXCR7 抗体)

IHC

ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed human pancreatic cancer cell line, using CXCR7, antibody at 1:50 dilution. (CXCR7 抗体)

VPA increases CXCR4 and CXCR7 gene and protein expression. (CXCR7 抗体)

CXCR7 co-localizes with EGFR. (CXCR7 抗体)

PLA

IF (cc)

The expression of CXCR7 in metastatic melanoma cells and clinical samples. (CXCR7 抗体)

IHC

Skeletal muscle cells-secreted VEGF promotes the upregulation of CXCR7 in MSCs. (CXCR7 抗体)

PDGFRα and PDGFRβ are essential for VEGF-induced CXCR7 expression in MSCs. (CXCR7 抗体)

Blockage of CXCR7 inhibits VEGF-mediated vasculogenesis by MSCs. (CXCR7 抗体)

The SDF-1/CXCR7 axis promotes vasculogenesis by MSCs. (CXCR7 抗体)

16 images

(7 references)

产品编号 ABIN2857021

发货至: 中国

Quick Overview for CXCR7 抗体 (ABIN2857021)

抗原

See all CXCR7 抗体

CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

适用

人

宿主

兔

克隆类型

多克隆

标记

This CXCR7 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

质量等级

KO Validated

交叉反应

人, 小鼠

产品特性

Rabbit Polyclonal antibody to CXCR7 (C-X-C chemokine receptor type 7)
CXCR7 antibody [C1C2], Internal

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human CXCR7. The exact sequence is proprietary.

亚型

IgG
anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody
CXCR7 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (Internal Region) antibody
CXCR7 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 151-250) antibody
CXCR7 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 311-360) antibody
CXCR7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (Extracellular Domain) antibody
CXCR7 适用: 人, 大鼠, 小鼠, 犬, Cow, Pig, 马, Bat, Hamster, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (Cytoplasmic Domain) antibody
CXCR7 适用: 人, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody
CXCR7 适用: 人 FACS 宿主: 小鼠 Monoclonal 10D1-J16 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 50-150) antibody
CXCR7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 330-358), (C-Term) antibody
CXCR7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB23520 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 330-358) antibody
CXCR7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Validatio: KO/KD, Orthogonal

限制

仅限研究用
状态

Liquid

浓度

0.92 mg/mL

缓冲液

1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Wei, Huang, Hsieh, Lin, Shyu, Chen, Hsieh: "Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling." in: Cell death & disease, Vol. 11, Issue 5, pp. 307, (2020) (PubMed).

Liu, Song, Setroikromo, Chen, Hu, Chen, van der Wekken, Melgert, Timens, van den Berg, Saber, Haisma: "CX Chemokine Receptor 7 Contributes to Survival of KRAS-Mutant Non-Small Cell Lung Cancer upon Loss of Epidermal Growth Factor Receptor." in: Cancers, Vol. 11, Issue 4, (2019) (PubMed).

Xu, Tang, Wang, Liu, Fu, Luo: "CXCR7 promotes melanoma tumorigenesis via Src kinase signaling." in: Cell death & disease, Vol. 10, Issue 3, pp. 191, (2019) (PubMed).

Tam, Ko, Koon, Cheng, Lok, Lau, Leung, Fung, Chan, Lau: "Identification of Target Genes Involved in Wound Healing Angiogenesis of Endothelial Cells with the Treatment of a Chinese 2-Herb Formula." in: PLoS ONE, Vol. 10, Issue 10, pp. e0139342, (2016) (PubMed).

Liu, Carson-Walter, Walter: "Chemokine receptor CXCR7 is a functional receptor for CXCL12 in brain endothelial cells." in: PLoS ONE, Vol. 9, Issue 8, pp. e103938, (2015) (PubMed).

Salazar, Muñoz, Kallifatidis, Singh, Jordà, Lokeshwar: "The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation." in: Molecular cancer, Vol. 13, pp. 198, (2014) (PubMed).

Singh, Lokeshwar: "The IL-8-regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth." in: Cancer research, Vol. 71, Issue 9, pp. 3268-77, (2011) (PubMed).
抗原

CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

别名

atypical chemokine receptor 3

背景

This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

Cellular Localization: Cell membrane

分子量

41 kDa

基因ID

57007

UniProt

P25106

途径

Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling