GPBAR1 抗体 (C-Term)
This anti-GPBAR1 antibody is a 兔 多克隆 antibody detecting GPBAR1 in WB 和 IHC (p). Suitable for 人.
Quick Overview for GPBAR1 抗体 (C-Term) (ABIN2857020)
抗原
See all GPBAR1 抗体
GPBAR1
(G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
适用
人
宿主
兔
克隆类型
多克隆
标记
This GPBAR1 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- C-Term
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to TGR5 (G protein-coupled bile acid receptor 1)
TGR5 antibody [C2C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TGR5. The exact sequence is proprietary.
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亚型
- IgG
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anti-G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) (Cytoplasmic Domain) antibody
GPBAR1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
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别名
- G protein-coupled bile acid receptor 1
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背景
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This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
Cellular Localization: Cell membrane, Multi-pass membrane protein -
分子量
- 35 kDa
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基因ID
- 151306
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UniProt
- Q8TDU6
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途径
- WNT signaling, Hormone Transport, Sensory Perception of Sound
抗原
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