CASP14 抗体 (C-Term)
(1 reference)Quick Overview for CASP14 抗体 (C-Term) (ABIN2856832)
抗原
See all CASP14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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产品特性
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Rabbit polyclonal antibody to Caspase 14 (caspase 14, apoptosis-related cysteine peptidase)
Caspase 14 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Caspase 14. The exact sequence is proprietary.
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亚型
- IgG
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anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 133-242) antibody
CASP14 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C9 unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 223-242) antibodyCASP14 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 17-248) antibodyCASP14 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-242) antibodyCASP14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 171-230) antibodyCASP14 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-246) antibodyCASP14 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 155-242) antibodyCASP14 适用: 人, 小鼠, 大鼠 ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-242) antibodyCASP14 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 59-93) antibodyCASP14 适用: 人 WB 宿主: 兔 Polyclonal RB52885 unconjugated
anti-Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14) (AA 1-242) antibodyCASP14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431 , PC-3
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes." in: Iranian journal of basic medical sciences, Vol. 19, Issue 1, pp. 28-33, (2016) (PubMed).
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: "Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes." in: Iranian journal of basic medical sciences, Vol. 19, Issue 1, pp. 28-33, (2016) (PubMed).
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- CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
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别名
- caspase 14
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背景
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This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
Cellular Localization: Cytoplasm , Nucleus -
分子量
- 28 kDa
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基因ID
- 23581
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UniProt
- P31944
抗原
-
