SSRP1 抗体
Quick Overview for SSRP1 抗体 (ABIN2856824)
抗原
See all SSRP1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
特异性
- Knockdown/Knockout validation was supported by references (PMID:26990993)
-
交叉反应
- 人
-
产品特性
-
Rabbit polyclonal antibody to SSRP1 (structure specific recognition protein 1)
SSRP1 antibody [N1N3] -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human SSRP1. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-Structure Specific Recognition Protein 1 (SSRP1) antibody
SSRP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 1-300) antibodySSRP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 1-242) antibodySSRP1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (N-Term) antibodySSRP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人 WB 宿主: 小鼠 Monoclonal 10D7 unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人 WB 宿主: 小鼠 Monoclonal 3E4 unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 611-660) antibodySSRP1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, Pig, 猴, Bat, Drosophila melanogaster, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 503-552) antibodySSRP1 适用: 人, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: Molt-4 , 293T , A431 , HeLa , HepG2 , Jurkat
Validation: KO/KD
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
-
别名
- structure specific recognition protein 1
-
背景
-
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
Cellular Localization: Nucleus -
分子量
- 81 kDa
-
基因ID
- 6749
-
UniProt
- Q08945
-
途径
- Chromatin Binding
抗原
-
