SSRP1 抗体
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Quick Overview for SSRP1 抗体 (ABIN2856824)
抗原
See all SSRP1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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特异性
- Knockdown/Knockout validation was supported by references (PMID:26990993)
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交叉反应
- 人
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产品特性
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Rabbit polyclonal antibody to SSRP1 (structure specific recognition protein 1)
SSRP1 antibody [N1N3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human SSRP1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 1-300) antibody
SSRP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 1-242) antibodySSRP1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB350 unconjugated Recombinant Antibody
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (N-Term) antibodySSRP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人 WB 宿主: 小鼠 Monoclonal 3E4 unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) antibodySSRP1 适用: 人 WB 宿主: 小鼠 Monoclonal 10D7 unconjugated
anti-Structure Specific Recognition Protein 1 (SSRP1) (AA 503-552) antibodySSRP1 适用: 人, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Molt-4 , 293T , A431 , HeLa , HepG2 , Jurkat
Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
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别名
- structure specific recognition protein 1
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背景
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The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
Cellular Localization: Nucleus -
分子量
- 81 kDa
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基因ID
- 6749
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UniProt
- Q08945
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途径
- Chromatin Binding
抗原
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