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CAMK2D 抗体

This anti-CAMK2D antibody is a 兔 多克隆 antibody detecting CAMK2D in WB, IF, IHC (p), ICC 和 IP. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2856806
发货至: 中国

Quick Overview for CAMK2D 抗体 (ABIN2856806)

抗原

See all CAMK2D 抗体
CAMK2D (Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D))

适用

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宿主

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克隆类型

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多克隆

标记

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This CAMK2D antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)

质量等级

KO Validated
  • 特异性

    Cross-reactivity may occur with other CaM kinase II subunits.

    交叉反应

    人, 小鼠, 兔, 大鼠, 斑马鱼

    产品特性

    Rabbit Polyclonal antibody to CaMKII delta (calcium/calmodulin-dependent protein kinase II delta)
    CaMKII delta antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human CaMKII delta. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:50000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A549 , H1299 , HCT116 , 293T , A431 , HeLa , HepG2 , mouse brain , rat brain

    Validation: KO/KD, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.62 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Liu, Zhong, Zhou, Yang, Tan, Li, Gao, Sun, Li, Jin, Cao, Yuan, Liu, Liang, Li, Du, Zhao, Xue, Zhao, Song, Ling, Li: "Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity." in: Cell proliferation, Vol. 53, Issue 3, pp. e12783, (2020) (PubMed).

    Li, Liu, Li, Zheng, Xu, Liu, Sun, Li, Ji, Liu, Zhang, Zhao, Du, Liu, Zhong, Sun, Wang, Song, Zhang, Qin, Ling, Wang, Li: "TMCO1-mediated Ca2+ leak underlies osteoblast functions via CaMKII signaling." in: Nature communications, Vol. 10, Issue 1, pp. 1589, (2019) (PubMed).

    Xu, Wang, Zhang, Gong, Gutierrez Cortes, Zhu, Yoon, Tian, Wang: "CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation." in: Nature communications, Vol. 7, pp. 13189, (2016) (PubMed).

  • 抗原

    CAMK2D (Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D))

    别名

    calcium/calmodulin dependent protein kinase II delta

    背景

    The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.

    分子量

    56 kDa

    基因ID

    817

    UniProt

    Q13557

    途径

    WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration
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