CAMK2D 抗体
Quick Overview for CAMK2D 抗体 (ABIN2856806)
抗原
See all CAMK2D 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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特异性
- Cross-reactivity may occur with other CaM kinase II subunits.
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交叉反应
- 人, 小鼠, 兔, 大鼠, 斑马鱼
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产品特性
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Rabbit Polyclonal antibody to CaMKII delta (calcium/calmodulin-dependent protein kinase II delta)
CaMKII delta antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CaMKII delta. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:50000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A549 , H1299 , HCT116 , 293T , A431 , HeLa , HepG2 , mouse brain , rat brain
Validation: KO/KD, Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.62 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity." in: Cell proliferation, Vol. 53, Issue 3, pp. e12783, (2020) (PubMed).
: "TMCO1-mediated Ca2+ leak underlies osteoblast functions via CaMKII signaling." in: Nature communications, Vol. 10, Issue 1, pp. 1589, (2019) (PubMed).
: "CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation." in: Nature communications, Vol. 7, pp. 13189, (2016) (PubMed).
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Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity." in: Cell proliferation, Vol. 53, Issue 3, pp. e12783, (2020) (PubMed).
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- CAMK2D (Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D))
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别名
- calcium/calmodulin dependent protein kinase II delta
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背景
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The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
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分子量
- 56 kDa
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基因ID
- 817
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UniProt
- Q13557
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途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration
抗原
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