BBS10 抗体
Quick Overview for BBS10 抗体 (ABIN2856679)
抗原
See all BBS10 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to BBS10 (Bardet-Biedl syndrome 10)
BBS10 antibody [N2C1], Internal -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human BBS10. The exact sequence is proprietary.
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亚型
- IgG
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anti-Bardet-Biedl Syndrome 10 (BBS10) (Internal Region) antibody
BBS10 适用: 人, 小鼠, 斑马鱼 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 10 (BBS10) (AA 474-723) antibodyBBS10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 10 (BBS10) (AA 515-544), (C-Term) antibodyBBS10 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB24715 unconjugated
anti-Bardet-Biedl Syndrome 10 (BBS10) (C-Term) antibodyBBS10 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- BBS10 (Bardet-Biedl Syndrome 10 (BBS10))
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别名
- Bardet-Biedl syndrome 10
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背景
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This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.
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分子量
- 81 kDa
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基因ID
- 79738
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UniProt
- Q8TAM1
抗原
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