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IL-24 抗体 (C-Term)

This anti-IL-24 antibody is a 兔 多克隆 antibody detecting IL-24 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN2856609
发货至: 中国

Quick Overview for IL-24 抗体 (C-Term) (ABIN2856609)

抗原

See all IL-24 (IL24) 抗体
IL-24 (IL24) (Interleukin 24 (IL24))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL-24 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    交叉反应

    产品特性

    Rabbit polyclonal antibody to Interleukin-24 (interleukin 24)
    Interleukin-24 antibody [C2C3], C-term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IL24. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A431

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.46 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    IL-24 (IL24) (Interleukin 24 (IL24))

    别名

    interleukin 24

    背景

    This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27 kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Cellular Localization: Secreted

    分子量

    24 kDa

    基因ID

    11009

    UniProt

    Q13007

    途径

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
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