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INHBA 抗体 (C-Term)

This anti-INHBA antibody is a 兔 多克隆 antibody detecting INHBA in WB, ICC, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN2856600
发货至: 中国
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中国
北京 101111
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Quick Overview for INHBA 抗体 (C-Term) (ABIN2856600)

抗原

See all INHBA 抗体
INHBA (Inhibin, beta A (INHBA))

适用

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宿主

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克隆类型

  • 81
  • 16
多克隆

标记

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This INHBA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 抗原表位

    • 8
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    C-Term

    交叉反应

    产品特性

    Rabbit Polyclonal antibody to Inhibin beta A (inhibin, beta A)
    Inhibin beta A antibody

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Inhibin beta A. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.66 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    INHBA (Inhibin, beta A (INHBA))

    别名

    inhibin subunit beta A

    背景

    The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

    Cellular Localization: Secreted

    分子量

    47 kDa

    基因ID

    3624

    UniProt

    P08476

    途径

    Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy
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