H2AFZ 抗体 (N-Term)
(1 reference)Quick Overview for H2AFZ 抗体 (N-Term) (ABIN2856590)
抗原
See all H2AFZ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人, 斑马鱼
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产品特性
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Rabbit Polyclonal antibody to Histone H2A.Z (H2A histone family, member Z)
Histone H2A.Z antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histone H2A.Z. The exact sequence is proprietary.
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亚型
- IgG
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anti-H2A Histone Family, Member Z (H2AFZ) (acLys4) antibody
H2AFZ 适用: 人 WB, ELISA, IF, ICC, ChIP, IP 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (acLys7) antibodyH2AFZ 适用: 人 WB, ELISA, IF, ICC, ChIP, IP 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (C-Term) antibodyH2AFZ 适用: 人 WB, IF, ICC, ChIP, ChIP-seq, DB 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (C-Term) antibodyH2AFZ 适用: 人 WB, IF, ICC, ChIP, IP, IHC (p), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (C-Term) antibodyH2AFZ 适用: 人 WB, IF, ChIP, ChIP-seq, DB, CUT&RUN, CUT&Tag 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (acLys11) antibodyH2AFZ 适用: 人 WB, ELISA, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (meLys4) antibodyH2AFZ 适用: 人 ELISA, IF, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) antibodyH2AFZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) antibodyH2AFZ 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Monoclonal 7G8 unconjugated
anti-H2A Histone Family, Member Z (H2AFZ) (AA 1-128) antibodyH2AFZ 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Jurkat
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.52 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage." in: Molecular cell, Vol. 72, Issue 5, pp. 888-901.e7, (2018) (PubMed).
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: "The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage." in: Molecular cell, Vol. 72, Issue 5, pp. 888-901.e7, (2018) (PubMed).
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- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
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别名
- H2A histone family member Z
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背景
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Cellular Localization: Nucleus -
分子量
- 14 kDa
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基因ID
- 3015
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UniProt
- P0C0S5
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途径
- Telomere Maintenance
抗原
-
