GSTA1 抗体
Quick Overview for GSTA1 抗体 (ABIN2856555)
抗原
See all GSTA1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Based on sequence homology, this antibody may cross react with other GSTA family members.
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit Polyclonal antibody to GSTA1 (glutathione S-transferase alpha 1)
GSTA1 antibody -
纯化方法
- Affinity purified by Protein A.
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免疫原
- Recombinant protein corresponding to human GSTA1
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亚型
- IgG
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anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 2-222) antibody
GSTA1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 1-222) antibodyGSTA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 2-222) antibodyGSTA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 1-222) antibodyGSTA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 1-222) antibodyGSTA1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 2-223) antibodyGSTA1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 2-222) antibodyGSTA1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (N-Term) antibodyGSTA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) antibodyGSTA1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB22670 unconjugated
anti-Glutathione S-Transferase alpha 1 (GSTA1) (AA 1-222) antibodyGSTA1 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 2F7 unconjugated
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应用备注
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Mouse liver , HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 6 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- GSTA1 (Glutathione S-Transferase alpha 1 (GSTA1))
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别名
- glutathione S-transferase alpha 1
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背景
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Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Cellular Localization: Cytoplasm -
分子量
- 26 kDa
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基因ID
- 2938
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UniProt
- P08263
抗原
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