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SPOP-B 抗体 (Center)

The 兔 多克隆 anti-SPOP-B antibody (ABIN2856462) specifically detects SPOP-B in WB 和 IHC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN2856462
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SPOP-B 抗体 (Center) (ABIN2856462)

抗原

See all SPOP-B 抗体
SPOP-B (Speckle-Type POZ Protein (SPOP-B))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This SPOP-B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Center

    交叉反应

    大鼠, Xenopus tropicalis, 猕猴, 牛

    交叉反应 (详细)

    Rat (100 %), Xenopus Tropicalis (100 %), Rhesus Monkey (100 %), Bovine (100 %)

    产品特性

    Rabbit Polyclonal antibody to SPOP (speckle-type POZ protein)
    SPOP antibody [N1C1]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human SPOP. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    Suggested dilution Reference Immunohistochemistry Assay-dependent dilution Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunohistochemistryAssay-dependent dilution Western blot1:500-1:3000*

    说明

    Positive Control: 293T , Raji , mouse brain

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    SPOP-B (Speckle-Type POZ Protein (SPOP-B))

    别名

    SPOP

    背景

    This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.

    Cellular Localization: Nucleus

    分子量

    42 kDa

    基因ID

    8405
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