SPOP-B 抗体 (Center)
Quick Overview for SPOP-B 抗体 (Center) (ABIN2856462)
抗原
See all SPOP-B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Center
-
交叉反应
- 大鼠, Xenopus tropicalis, 猕猴, 牛
-
交叉反应 (详细)
- Rat (100 %), Xenopus Tropicalis (100 %), Rhesus Monkey (100 %), Bovine (100 %)
-
产品特性
-
Rabbit Polyclonal antibody to SPOP (speckle-type POZ protein)
SPOP antibody [N1C1] -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human SPOP. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- Suggested dilution Reference Immunohistochemistry Assay-dependent dilution Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunohistochemistryAssay-dependent dilution Western blot1:500-1:3000*
-
说明
-
Positive Control: 293T , Raji , mouse brain
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
-
别名
- SPOP
-
背景
-
This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
Cellular Localization: Nucleus -
分子量
- 42 kDa
-
基因ID
- 8405
抗原
-