SKP1 抗体
Quick Overview for SKP1 抗体 (ABIN2856416)
抗原
See all SKP1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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产品特性
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Rabbit Polyclonal antibody to SKP1 (S-phase kinase-associated protein 1)
SKP1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human SKP1. The exact sequence is proprietary.
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亚型
- IgG
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anti-S-Phase Kinase-Associated Protein 1 (SKP1) antibody
SKP1 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (Internal Region) antibodySKP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 53-160) antibodySKP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H8 unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-163) antibodySKP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-163) antibodySKP1 适用: 人, 大鼠, 猴, 小鸡, Cow, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-160) antibodySKP1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 81-163) antibodySKP1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-163) antibodySKP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 2-163) antibodySKP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-110) antibodySKP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: NIH-3T3 , A549 , H1299 , HCT116 , MCF-7
Validation: Overexpression
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
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别名
- S-phase kinase associated protein 1
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背景
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This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
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分子量
- 19 kDa
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基因ID
- 6500
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UniProt
- P63208
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途径
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases
抗原
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