RGS14 抗体 (C-Term)
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北京 101111
Quick Overview for RGS14 抗体 (C-Term) (ABIN2856368)
抗原
See all RGS14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to RGS14 (regulator of G-protein signaling 14)
RGS14 antibody [C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RGS14. The exact sequence is proprietary.
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亚型
- IgG
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anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 1-566) antibody
RGS14 适用: 人 ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (Internal Region) antibodyRGS14 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 230-510) antibodyRGS14 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 230-510) antibodyRGS14 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (C-Term) antibodyVerified RGS14 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 1-566) antibodyRGS14 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 201-250) antibodyRGS14 适用: 人, 小鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 14 (RGS14) (AA 504-516) antibodyRGS14 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Jurkat
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.93 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
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别名
- regulator of G protein signaling 14
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背景
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This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Cellular Localization: Membrane -
分子量
- 61 kDa
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基因ID
- 10636
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UniProt
- O43566
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
抗原
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