MTA2 抗体 (C-Term)
Quick Overview for MTA2 抗体 (C-Term) (ABIN2856347)
抗原
See all MTA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 人
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产品特性
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Rabbit polyclonal antibody to MTA2 (metastasis associated 1 family, member 2)
MTA2 antibody [C3], C-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MTA2. The exact sequence is proprietary.
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亚型
- IgG
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anti-Metastasis Associated 1 Family, Member 2 (MTA2) antibody
MTA2 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 60-180) antibodyMTA2 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人, Cow, 马, 兔, 山羊, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 1-394) antibodyMTA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 516-544), (C-Term) antibodyMTA2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20031 unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 山羊, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 129-178) antibodyMTA2 适用: 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 398-447) antibodyMTA2 适用: 人, 斑马鱼, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 380-429) antibodyMTA2 适用: 小鼠, 大鼠, 犬, Cow, 马, 兔, 山羊, Pig, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T, A431
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.67 mg/mL
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缓冲液
- 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
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别名
- metastasis associated 1 family member 2
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背景
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This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
Cellular Localization: Nucleus -
分子量
- 75 kDa
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基因ID
- 9219
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UniProt
- O94776
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途径
- Chromatin Binding
抗原
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