RANGAP1 抗体 (N-Term)
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Quick Overview for RANGAP1 抗体 (N-Term) (ABIN2856335)
抗原
See all RANGAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人
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产品特性
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Rabbit Polyclonal antibody to RanGAP1 (Ran GTPase activating protein 1)
RanGAP1 antibody [N1], N-term -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human RanGAP1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Ran GTPase Activating Protein 1 (RANGAP1) antibody
RANGAP1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ran GTPase Activating Protein 1 (RANGAP1) (AA 1-587) antibodyRANGAP1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Ran GTPase Activating Protein 1 (RANGAP1) (AA 398-587) antibodyRANGAP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ran GTPase Activating Protein 1 (RANGAP1) (N-Term) antibodyRANGAP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ran GTPase Activating Protein 1 (RANGAP1) (AA 359-587) antibodyRANGAP1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4F9E2 unconjugated
anti-Ran GTPase Activating Protein 1 (RANGAP1) (N-Term) antibodyVerified RANGAP1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ran GTPase Activating Protein 1 (RANGAP1) antibodyRANGAP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Ran GTPase Activating Protein 1 (RANGAP1) (AA 20-49), (N-Term) antibodyRANGAP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33892 unconjugated
anti-Ran GTPase Activating Protein 1 (RANGAP1) antibodyRANGAP1 适用: 人, 大鼠, 犬 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Ran GTPase Activating Protein 1 (RANGAP1) antibodyRANGAP1 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB1595 unconjugated Recombinant Antibody
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
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别名
- Ran GTPase activating protein 1
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背景
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RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88 % identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.
Cellular Localization: Cytoplasm , Nucleus membrane, Peripheral membrane protein, Cytoplasmic side , Kinetochore (By similarity) -
分子量
- 64 kDa
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基因ID
- 5905
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UniProt
- P46060
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途径
- M Phase, Protein targeting to Nucleus
抗原
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