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DCLK2 抗体

This anti-DCLK2 antibody is a 兔 多克隆 antibody detecting DCLK2 in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN2856229
发货至: 中国

Quick Overview for DCLK2 抗体 (ABIN2856229)

抗原

See all DCLK2 抗体
DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

适用

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宿主

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克隆类型

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多克隆

标记

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This DCLK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 交叉反应

    产品特性

    Rabbit polyclonal antibody to DCAMKL2 (doublecortin-like kinase 2)
    DCAMKL2 antibody [N2C2], Internal

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human DCAMKL2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A549 , H1299 , HCT116

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.16 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

    别名

    doublecortin like kinase 2

    背景

    This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

    分子量

    84 kDa

    基因ID

    166614

    UniProt

    Q8N568
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