Hexokinase 1 抗体
(1 reference)Quick Overview for Hexokinase 1 抗体 (ABIN2856070)
抗原
See all Hexokinase 1 (HK1) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 斑马鱼
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产品特性
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Rabbit Polyclonal antibody to HXK I (hexokinase 1)
Hexokinase 1 antibody -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Hexokinase 1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Hexokinase 1 (HK1) (AA 413-540) antibody
HK1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 1 (HK1) antibodyKO Validated HK1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Monoclonal unconjugated
anti-Hexokinase 1 (HK1) (AA 20-300) antibodyHK1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 1 (HK1) (AA 1-916) antibodyHK1 适用: 人 WB, IP, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Hexokinase 1 (HK1) antibodyHK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3A10 unconjugated
anti-Hexokinase 1 (HK1) (AA 78-108), (N-Term) antibodyHK1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3921-RB3922 unconjugated
anti-Hexokinase 1 (HK1) antibodyHK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 7A7 unconjugated
anti-Hexokinase 1 (HK1) (AA 1-917), (N-Term) antibodyHK1 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 4D7 unconjugated
anti-Hexokinase 1 (HK1) (AA 80-215) antibodyHK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 1 (HK1) (AA 1-916) antibodyHK1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431 , H1299 , HeLaS3 , HepG2
Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 16717, (2019) (PubMed).
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: "The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 16717, (2019) (PubMed).
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- Hexokinase 1 (HK1)
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别名
- hexokinase 1
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背景
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Cellular Localization: Mitochondrion outer membrane -
分子量
- 102 kDa
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基因ID
- 3098
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UniProt
- P19367
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途径
- Carbohydrate Homeostasis, Warburg Effect
抗原
-
